56379-89-6 Usage
Description
Z-PHE-OH, with the molecular formula C16H19NO3, is a phenylalanine derivative and a white crystalline solid. It is characterized by a melting point of 136-139°C and slight solubility in water, with solubility in organic solvents like ethanol and methanol. Known by its IUPAC name, (2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid, Z-PHE-OH is an essential component in the synthesis of pharmaceuticals and serves as a building block in organic chemistry. It is also widely utilized in the research and development of peptide-based drugs and biologically active compounds.
Uses
Used in Pharmaceutical Synthesis:
Z-PHE-OH is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Organic Chemistry:
As a building block, Z-PHE-OH is utilized in organic chemistry for the creation of complex organic molecules and compounds.
Used in Research and Development of Peptide-based Drugs:
Z-PHE-OH is employed as a crucial component in the research and development of peptide-based drugs, aiding in the discovery and design of innovative treatments.
Used in Biologically Active Compounds Development:
Z-PHE-OH is also used in the development of biologically active compounds, which have potential applications in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 56379-89-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,7 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 56379-89:
(7*5)+(6*6)+(5*3)+(4*7)+(3*9)+(2*8)+(1*9)=166
166 % 10 = 6
So 56379-89-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO4/c18-15(19)14(11-12-7-3-1-4-8-12)17-16(20)21-13-9-5-2-6-10-13/h1-10,14H,11H2,(H,17,20)(H,18,19)
56379-89-6Relevant articles and documents
Revolutionary phosgene-free synthesis of α-amino acid N-carboxyanhydrides using diphenyl carbonate based on activation of α-amino acids by converting into imidazolium salts
Koga, Koichi,Sudo, Atsushi,Endo, Takeshi
experimental part, p. 4351 - 4355 (2011/11/30)
The phosgene-free synthesis of α-amino acid n-carboxyanhydrides using diphenyl carbonate based on activation of α-amino acids by converting into imidazolium salts was reported. 1-Ethyl-3-methylimidazolium bromide (4.77 g, 25.0 mmol) was dissolved in water (25 mL) and was passed through a column of Amberlite IRA 400 CL (50 cm3) using 250 mL of water as an eluent to synthesize amino acid imidazolium salt. A solution of L-phenylalanine imidazolium salt (550 mg, 2.0 mmol) in acetonitrile (15 mL) was added dropwise to a solution of diphenyl-carbonate (427 mg, 2.00 mmol) in acetonitrile (5 mL) at room temperature, and the reaction mixture was stirred at room temperature to synthesize urethane derivative. The results showed that all of the obtained imidazolium salts were soluble in chloroform, dichloromethane, 2-butanone acetonitrile, and not soluble in tetrahydrofuran.
