5638-60-8

Basic information

• Product Name: 1,4-oxazepane(SALTDATA: HCl)
• Synonyms: 1,4-oxazepane(SALTDATA: HCl);1,4-Oxazepine, hexahydro-;1,4-oxazepane(SALTDATA
• CAS NO: 5638-60-8
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.15
• Mol File: 5638-60-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 174-175 °C
• Boiling Point: 66 °C(Press: 12 Torr)
• Appearance: /
• Density: 0.909±0.06 g/cm3(Predicted)
• PKA: 10.01±0.20(Predicted)
• CAS DataBase Reference: 1,4-oxazepane(SALTDATA: HCl)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-oxazepane(SALTDATA: HCl)(5638-60-8)
• EPA Substance Registry System: 1,4-oxazepane(SALTDATA: HCl)(5638-60-8)

Safety Data

• Hazardous Substances Data: 5638-60-8(Hazardous Substances Data)

Usage

General Description

1,4-oxazepane, also known as tetrahydro-1,4-oxazepine, is a chemical compound that is commonly used as a building block for various pharmaceutical compounds. The HCl salt form of 1,4-oxazepane is a white crystalline powder that is soluble in water and has a molecular weight of 177.66 g/mol. It is known for its potential as a central nervous system depressant and has been studied for its potential therapeutic applications in the treatment of anxiety and depression. However, due to its psychoactive properties, it is also considered a controlled substance and is subject to regulation in various regions. Overall, 1,4-oxazepane HCl is a versatile compound with both therapeutic and regulatory implications in the pharmaceutical industry.

Upstream product

• 10341-26-1 tetrahydro-(2H)-1,4-oxazepin-5-one 
• 178312-62-4 homomorpholine hydrochloride 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 61128-73-2 tetrahydropyran-4-one oxime 

Downstream Products

• 1190058-25-3 4-(2-hydroxypropan-2-yl)-N-(2-methyl-7-(1,4-oxazepan-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl)benzamide 
• 1187466-14-3 (2-chloro-5-phenyl-thiophen-3-yl)-[1,4]oxazepan-4-yl-methanone 
• 1195780-00-7 6-[1-cyclobutyl-4-(1,4-oxazepan-4-ylcarbonyl)-1H-pyrazol-5-yl]-13-cyclohexyl-3-methoxy-N-[(1-methylethyl)sulfonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide 
• 1205600-17-4 [1,4]oxazepane-4-carboxylic acid {1-[5-(4-fluorobenzoyl)-4-trifluoromethyl-thiazol-2-ylcarbamoyl]-1-methyl-ethyl}-amide 
• 887931-82-0 C₁₉H₂₆N₄O₃ 
• 1228098-23-4 C₁₇H₂₆N₂O₃ 
• 1228305-09-6 C₁₄H₁₉NO₃ 
• 1228244-79-8 C₁₉H₂₄N₄O₂ 
• 1391926-39-8 C₂₉H₃₃N₇O₄ 
• 116885-98-4 (piperidinyl-1)-4 butanoate d'ethyle 
• 5463-76-3 γ-piperidinobutyric acid hydrochloride 
• 1425050-99-2 C₂₄H₂₅N₅O₃ 
• 1464151-01-6 4-(6-(4-(1,4-oxazepane-4-carbonyl)phenyl)imidazo[1,2-b]pyridazin-3-yl)benzonitrile 
• 1464151-34-5 4-(6-(4-(1,4-oxazepane-4-yl)carbonyl)phenylimidazo[1,2-a]pyridin-3-yl)benzonitrile 

Relevant articles and documents

NOVEL TRIAZINE COMPOUNDS

The present invention relates to novel triazine compounds of formula (1), methods of their preparation, pharmaceutical compositions containing these compounds and the use of these compounds to treat proliferative disorders such as tumors and cancers and also other conditions and disorders related to or associated with dysregulation of PI3 Kinases, PI3 Kinase pathway, mTOR and/ or the mTOR pathway.

FIVE-MEMBERED HETEROCYCLIC DERIVATIVE

The present invention relates to a compound represented by formula (I): a salt of the compound, or a solvate of the compound or the salt; a drug containing any of the compounds, the salts, and the solvates; a preventive and/or therapeutic agent for an ischemic disease containing any of the compounds, the salts, and the solvates; and a platelet coagulation inhibitor containing any of the compounds, the salts, and the solvates. The compound of the present invention is useful as a strong platelet coagulation inhibitor without inhibiting COX-1 or COX-2.

Quinolinecarboxamides as antiviral agents

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.