56380-59-7

Basic information

• Product Name: 1,3-Dithiolane-2-carbonyl chloride (9CI)
• Synonyms: 1,3-Dithiolane-2-carbonyl chloride (9CI)
• CAS NO: 56380-59-7
• Molecular Formula: C₄H₅ClOS₂
• Molecular Weight: 168.6649
• Product Categories: ACIDHALIDE
• Mol File: 56380-59-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 82 °C(Press: 0.9 Torr)
• Appearance: /
• Density: 1.482±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,3-Dithiolane-2-carbonyl chloride (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dithiolane-2-carbonyl chloride (9CI)(56380-59-7)
• EPA Substance Registry System: 1,3-Dithiolane-2-carbonyl chloride (9CI)(56380-59-7)

Safety Data

• Hazardous Substances Data: 56380-59-7(Hazardous Substances Data)

Usage

Chemical structure

A 1,3-dithiolane ring with a carbonyl chloride group attached to the 2nd carbon

Reactivity

Highly reactive

Applications

a. Building block for pharmaceuticals and organic compounds
b. Formation of carbon-sulfur bonds in organic molecules
c. Synthesis of thiolactones, important intermediates in organic chemistry

Electrophilic nature

Strong

Importance

Valuable tool for chemists and researchers in organic synthesis

Upstream product

• 5616-65-9 1,3-dithiolane-2-carboxylic acid 

Downstream Products

• 106723-98-2 2-Ethyl-3-phenyl-5,8-dithia-2-aza-spiro[3.4]octan-1-one 
• 106723-99-3 2-tert-butyl-3-phenyl-5,8-dithia-2-azaspiro<3,4>-octan-1-one 
• 106724-00-9 methyl-2-(1-oxo-3-phenyl-5,8-dithio-2-azaspiro<3,4>oct-2-yl)-acetate 
• 58216-29-8 2,3-diphenyl-5,8-dithio-2-azaspiro<3,4>octan-1-one 
• 106723-97-1 2-methyl-3-phenyl-5,8-dithio-2-azaspiro<3,4>octan-1-one 

Relevant articles and documents

A mild method for the replacement of a hydroxyl group by halogen. 1. Scope and chemoselectivity

α-Chloro-, bromo- and iodoenamines, which are readily prepared from the corresponding isobutyramides have been found to be excellent reagents for the transformation of a wide variety of alcohols or carboxylic acids into the corresponding halides. Yields are high and conditions are very mild thus allowing for the presence of sensitive functional groups. The reagents can be easily tuned allowing therefore the selective monohalogenation of polyhydroxylated molecules. The scope and chemoselectivity of the reactions have been studied and reaction mechanisms have been proposed.

3-(1,3-Dithian-2-yl)-4-cyclo-pentene-2-carboxylic acids, esters and amides

The invention relates to the stereoisomers of novel cyclopentene derivatives and to the preparation thereof. The cyclopentene derivatives are obtained by cycloaddition reaction between cyclopentadiene and a mono-or bis-thioalkyl (or aryl) ketene and r