56405-37-9

Basic information

• Product Name: 2-METHYL-3-SULFOPROPYL BENZOTHIAZOLIUM INNER SALT
• Synonyms: 2-METHYL-3-SULFOPROPYL BENZOTHIAZOLIUM INNER SALT;3-(2-METHYL-1,3-BENZOTHIAZOL-3-IUM-3-YL)PROPANE-1-SULFONATE;benzothiazolium,2-methyl-3-(3-sulfopropyl)-,hydroxide,innersalt;2-methyl-3-(3-sulphonatopropyl)benzothiazolium;2-METHYL-3-(3-SULFOPROPYL)BENZOTHIAZOLIUM BETAINE;2-Methyl-3-(3-sulfonatopropyl)benzothiazol-3-ium;2-Methyl-3-(gamma-sulfopropyl)benzothiazolium hydroxide inner salt;Benzothiazolium, 2-methyl-3-(3-sulfopropyl)-, inner salt
• CAS NO: 56405-37-9
• Molecular Formula: C₁₁H₁₃NO₃S₂
• Molecular Weight: 271.36
• EINECS: 260-157-8
• Mol File: 56405-37-9.mol
• Article Data: 18

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: Off-white crystalline powder
• Density: g/cm³
• CAS DataBase Reference: 2-METHYL-3-SULFOPROPYL BENZOTHIAZOLIUM INNER SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-3-SULFOPROPYL BENZOTHIAZOLIUM INNER SALT(56405-37-9)
• EPA Substance Registry System: 2-METHYL-3-SULFOPROPYL BENZOTHIAZOLIUM INNER SALT(56405-37-9)

Safety Data

• Hazardous Substances Data: 56405-37-9(Hazardous Substances Data)

Usage

General Description

2-Methyl-3-sulfopropyl benzothiazolium inner salt is a chemical compound that is commonly used as a fluorescent dye. It is often employed as a staining agent in biological research, particularly for visualizing and tracking certain proteins and nucleic acids in cells and tissues. Its fluorescent properties make it useful in various imaging techniques such as fluorescence microscopy and flow cytometry. Additionally, it has potential applications in medical diagnostics, environmental monitoring, and materials science. However, it is important to handle this chemical with care, as it may pose health risks if not used properly.

InChI:InChI=1/C11H13NO3S2/c1-9-12(7-4-8-17(13,14)15)10-5-2-3-6-11(10)16-9/h2-3,5-6H,4,7-8H2,1H3

Upstream product

• 1120-71-4 1,3-propanesultone 
• 120-75-2 2-Methylbenzothiazole 

Downstream Products

• 150196-53-5 2-{2-[4-(4,7,10,13-tetraoxa-1-azacyclopentadecyl)phenyl]ethenyl}-3-(3-sulphopropyl)benzothiazolium betaine 
• 150196-53-5 2-{2-[4-(4,7,10,13-tetraoxa-1-azacyclopentadecyl)phenyl]ethenyl}-3-(3-sulphopropyl)benzothiazolium betaine 
• 1208863-28-8 3-(4-nitrophenyl)-1-(3-propyl-2,3-dihydrobenzothiazol-2-ylidene)-5-[3-(3-sulfonatopropyl)benzothiazol-2-yl]pentamethinium 

Relevant articles and documents

A Reversible Photoacid Functioning in PBS Buffer under Visible Light

A metastable-state photoacid that can reversibly release a proton in PBS buffer (pH = 7.4) under visible light is reported. The design is based on the dual acid-base property and tautomerization of indazole. The quantum yield was as high as 0.73, and moderate light intensity (102 μmol·m2·s-1) is sufficient for the photoreaction. Reversible pH change of 1.7 units was demonstrated using a 0.1 mM aqueous solution. This type of photoacid is promising for control of proton-transfer processes in physiological conditions and may find applications in biomedical areas.

Near-infrared double-acid dye connected with oxygen ether chain as well as preparation method and application thereof

The invention discloses a near-infrared double-acid dye connected with an oxygen ether chain, and preparation and application thereof. The 2 -methylbenzothiazole derivative and dicyanovinyl modified semiaromatic acid derivative which is linked with an oxygen ether chain is prepared from a raw material. The near-infrared both-side acid dye has good stability and excellent optical performance, and especially the introduction of a sulfonic acid group and an oxygen ether chain can enhance the water solubility of the dye. When the near-infrared double-acid dye is used for detection G - quadruplex, G - quadruplex can interact with the dye molecules, and the change of the dye absorption spectrum and the fluorescence spectrum is caused while G - quadruplex topological structure changes, so that the dye can be used as G - quadruplex. Fluorescent probes for detection.

An activatable probe for detecting alcoholic liver injuryviamultispectral optoacoustic tomography and fluorescence imaging

A probe has been developed for imaging alcoholic liver injury through detecting the overexpressed cytochrome P450 reductase in hypoxia in the hepatic region. Upon response to the enzyme, the activated probe displays turn-on fluorescence and near-infrared absorption and generates prominent optoacoustic signals.