56421-61-5 Usage
Chemical structure
A heterocyclic compound with a thiazole ring attached to a thiophene ring and an ethanone group.
Functional groups
Thiazole ring, thiophene ring, and ethanone group.
Classification
Heterocyclic compound.
Applications
Used in medicinal chemistry and organic synthesis.
Potential uses
Building block for the synthesis of pharmaceuticals or other bioactive compounds.
Biological activity
Its structure suggests that it may have potential biological activity, but further research and testing are necessary to determine its exact properties and potential uses.
Research and testing
Further research and testing may be required to fully understand its properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 56421-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,2 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56421-61:
(7*5)+(6*6)+(5*4)+(4*2)+(3*1)+(2*6)+(1*1)=115
115 % 10 = 5
So 56421-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NOS2/c1-6-9(7(2)12)14-10(11-6)8-4-3-5-13-8/h3-5H,1-2H3
56421-61-5Relevant articles and documents
Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase
Ronkin, Steven M.,Badia, Michael,Bellon, Steve,Grillot, Anne-Laure,Gross, Christian H.,Grossman, Trudy H.,Mani, Nagraj,Parsons, Jonathan D.,Stamos, Dean,Trudeau, Martin,Wei, Yunyi,Charifson, Paul S.
scheme or table, p. 2828 - 2831 (2010/08/19)
Bacterial DNA gyrase is an attractive target for the investigation of new antibacterial agents. Inhibitors of the GyrB subunit, which contains the ATP-binding site, are described in this communication. Novel, substituted 5-(1H-pyrazol-3-yl)thiazole compounds were identified as inhibitors of bacterial gyrase. Structure-guided optimization led to greater enzymatic potency and moderate antibacterial potency. Data are presented for the demonstration of selective enzyme inhibition of Escherichia coli GyrB over Staphlococcus aureus GyrB.
