56424-23-8

Basic information

• Product Name: 1-Phenyl-1,2,2,2-tetrafluoroethane, (1,2,2,2-Tetrafluoroethyl)benzene
• Synonyms: (1H-Perfluoroethyl)benzene;1-Phenyl-1,2,2,2-tetrafluoroethane, (1,2,2,2-Tetrafluoroethyl)benzene
• CAS NO: 56424-23-8
• Molecular Formula: C₈H₆F₄
• Molecular Weight: 178.1268528
• Mol File: 56424-23-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 128-129 °C
• Appearance: /
• Density: 1.229±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Phenyl-1,2,2,2-tetrafluoroethane, (1,2,2,2-Tetrafluoroethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-1,2,2,2-tetrafluoroethane, (1,2,2,2-Tetrafluoroethyl)benzene(56424-23-8)
• EPA Substance Registry System: 1-Phenyl-1,2,2,2-tetrafluoroethane, (1,2,2,2-Tetrafluoroethyl)benzene(56424-23-8)

Safety Data

• Hazardous Substances Data: 56424-23-8(Hazardous Substances Data)

Usage

General Description

1-Phenyl-1,2,2,2-tetrafluoroethane, also known as (1,2,2,2-Tetrafluoroethyl)benzene, is a chemical compound with the molecular formula C8H7F4. It is a colorless, odorless gas that is commonly used as a refrigerant and as a propellant in aerosol cans. It has low toxicity and is non-flammable, making it a popular choice for various industrial and household applications. However, it is a potent greenhouse gas with a high global warming potential, and efforts are being made to replace it with more environmentally friendly alternatives. While it has a relatively low reactivity, it can react with strong oxidizing agents and bases, and caution should be exercised when handling and storing this compound.

Upstream product

• 98-82-8 Isopropylbenzene 
• 116-15-4 perfluoropropylene 
• 395-00-6 (E/Z)-1-chloro-1,2-difluoro-2-phenylethene 
• 538-93-2 1-phenyl-2-methylpropane 
• 135-98-8 sec-Butylbenzene 
• 101-81-5 Diphenylmethane 
• 340-04-5 1-phenyl-2,2,2-trifluoromethylethanol 
• 13652-07-8 phenyltrifluorodiazoethane 
• 434-45-7 2,2,2-Trifluoroacetophenone 
• 13652-11-4 2,2,2‐trifluoro‐1‐phenylethan‐1‐one tosylhydrazone 

Downstream Products

• 447-14-3 1,2,2-trifluorostyrene 

Relevant articles and documents

Α, β, β-trifluorolactic of industrial manufacturing method (by machine translation)

PROBLEM TO BE SOLVED: To provide a method of producing industrially α,β,β-trifluorostyrenes. SOLUTION: The method of producing industrially the α,β,β-trifluorostyrenes includes a dehydrofluorination step of reacting α-aryl-α,β,β,β-tetrafluoroethanes with an alkali metal-bis(trimethylsilyl) amide, in the production of α,β,β-trifluorostyrenes, and an after-treatment step executed followed thereto to react a mixture containing the α,β,β-trifluorostyrenes of objective products and bis-(trimethylsilyl) amine of a byproduct with hydrogen fluoride, or a salt or a complex comprising an organic base and hydrogen fluoride. COPYRIGHT: (C)2012,JPO&INPIT

An efficient dehyrohalogenation method for the synthesis of α,β,β-trifluorostyrenes, α-chloro-β,β- difluorostyrenes and E-1-arylperfluoroalkenes

Dehydrofluorination of 1-aryl-1,2,2,2-tetrafluoroethanes (ArCHFCF 3) and 1-aryl-1-chloro-2,2,2-trifluoroethane (ArCHClCF3) using lithiumhexamethyldisilazide (LHMDS) in tetrahydrofuran (THF) at room temperature produced 1,2,2-trifluorostyrene and 1-chloro-2,2-difluorostyrene, respectively, in very good isolated yields. Dehydrofluorination of 1,2,2,3,3,3-hexafluoro-1-phenyl-propane (PhCHFCF2CF3) and 1,2,2,3,3,4,4,4-octafluoro-1-phenyl-butane (PhCHFCF2CF 2CF3) using LHMDS produced the corresponding substituted olefins (1-phenyl-1,2,3,3,3-pentafluoroprop-1-ene and 1-phenyl-1,2,3,3,4,4,4- pentafluorobut-1-ene) in good yield and high E-selectivity. Dehydrofluorination of 1-chloro-1-phenyl-2,2,3,3,3-pentafluoropropane (PhCHClCF2CF 3) and 1-chloro-1-phenyl-2,2,3,3,4,4,4-heptafluorobutane (PhCHClCF2CF2CF3) produced a mixture of the corresponding E and Z olefins (PhCClCFCF3 and PhCClCFCF 2CF3) in good yield.

Oxidative fluorination of S, Se and Te compounds

The synthesis and mechanism of formation of cis- and trans-Ph2SF4 is described. Starting compounds are Ph2S or Ph2SF2 and the oxidizing agent is XeF2 in the presence of Et4NCl. Also described is the synthesis of related chalcogen(IV and VI) fluorides such as t-butylSF3, difluorodibenzothiophene, PhSeF3, Ph2SeF2, PhSF5, p-MeC6H4SF5, PhSeF5, and PhTeF5. The reactions of Ph2S(O)F2 with alcohols and with the H2O-HF-glass system are briefly described.