56424-81-8 Usage
Structure
A benzene ring with a carboxyl group (-COOH) attached to the 2-position, an amino group (-NH2) attached to the 2-position of the ethoxy group (-OCH2CH3) attached to the 3-position.
Type of compound
Organic chemical compound, derivative of benzoic acid.
Groups present
Amino group, ethoxy group, and carboxyl group.
Usage
Intermediate in the synthesis of pharmaceuticals and agrochemicals.
Potential applications
In the field of materials science, specifically in the development of polymers and coatings.
Therapeutic properties
Studied for its potential in the treatment of inflammation and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 56424-81-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,2 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56424-81:
(7*5)+(6*6)+(5*4)+(4*2)+(3*4)+(2*8)+(1*1)=128
128 % 10 = 8
So 56424-81-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO4/c10-8(11)5-14-7-4-2-1-3-6(7)9(12)13/h1-4H,5H2,(H2,10,11)(H,12,13)
56424-81-8Relevant articles and documents
Synthesis and biological evaluation of 2-Phenoxyacetamide analogues, a novel class of potent and selective monoamine oxidase inhibitors
Shen, Wei,Yu, Shian,Zhang, Jiaming,Jia, Weizheng,Zhu, Qing
, p. 18620 - 18631 (2014)
Monoamine oxidases (EC 1.4.3.4; MAOs), a family of FAD-containing enzymes, is an important target for antidepressant drugs. In this paper, a series of 2-phenoxyacetamide analogues were synthesized, and their inhibitory potency towards monoamine oxidases A (MAO-A) and B (MAO-B) were evaluated using enzyme and cancer cell lysate. 2-(4-Methoxyphenoxy)acetamide (compound 12) (SI = 245) and (2-(4-((prop-2- ynylimino)methyl)phenoxy)acetamide (compound 21) (IC50MAO-A = 0.018 μM, IC50MAO-B = 0.07 μM) were successfully identified as the most specific MAO-A inhibitor, and the most potent MAO-A/-B inhibitor, respectively. The inhibitory activities of these two compounds in living cells were also further evaluated utilizing HepG2 and SHSY-5Y cell lysates.
