56464-19-8

Basic information

• Product Name: 1-(4-amino-1,2-dimethyl-5-phenyl-1H-pyrrol-3-yl)ethanone
• CAS NO: 56464-19-8
• Molecular Formula: C₁₄H₁₆N₂O
• Molecular Weight: 228.2896
• Mol File: 56464-19-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 383.1°C at 760 mmHg
• Flash Point: 185.5°C
• Density: 1.12g/cm³
• Vapor Pressure: 4.49E-06mmHg at 25°C
• Refractive Index: 1.585
• CAS DataBase Reference: 1-(4-amino-1,2-dimethyl-5-phenyl-1H-pyrrol-3-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-amino-1,2-dimethyl-5-phenyl-1H-pyrrol-3-yl)ethanone(56464-19-8)
• EPA Substance Registry System: 1-(4-amino-1,2-dimethyl-5-phenyl-1H-pyrrol-3-yl)ethanone(56464-19-8)

Safety Data

• Hazardous Substances Data: 56464-19-8(Hazardous Substances Data)

Usage

Structure

1-(4-amino-1,2-dimethyl-5-phenyl-1H-pyrrol-3-yl)ethanone

Type of compound

Organic compound

Derivative of

Pyrrole

Contains functional groups

Phenyl group, amino group, and ketone functional group

Applications

Pharmaceutical research, potential use in drug development, and organic synthesis

Current status

Properties and potential uses are under study and exploration

Upstream product

• 127394-90-5 4-acetyl-1,5-dimethyl-3-nitro-2-phenylpyrrole 
• 56464-15-4 4-(p-chlorobenzylidene)amino-2-methyl-5-phenylpyrrol-3-yl-methylketone 
• 127394-88-1 4-acetyl-5-methyl-3-nitro-2-phenylpyrrole 
• 13219-97-1 4-acetyl-5-methyl-2-phenylpyrrole 

Relevant articles and documents

About the Synthesis of N-1-Substituted 3-Aminopyrroles. A Comparison

A general method for the preparation of 3-amino-1-methylpyrroles in excellent yields is reported.The key step involves the N-methylation of the nitro derivatives 2, under phase transfer catalysis conditions.

Aminopyrrole derivatives

Pharmacologically-active aminopyrrole derivatives of the formula STR1 wherein: R is selected from hydrogen, (C1-4)alkyl, benzyl and chlorobenzyl; R1 is selected from hydrogen, (C1-4)alkyl, phenyl and phenyl substituted by a radical selected from methyl, ethyl, methoxy, ethoxy, benzyloxy, fluoro, chloro and bromo; R2 and R3 individually represent hydrogen or (C1-4)alkyl or, taken together, represent an isopropylidene, a benzylidene or a chlorobenzylidene radical; R4 is selected from (C2-4)alkanoyl; carbo(C1-3)alkoxy; benzoyl, benzoyl substituted by a radical selected from chloro, methoxy or ethoxy; carbamoyl, methylcarbamoyl and phenyl carbamoyl; R5 is selected from hydrogen, (C1-4)alkyl, carbo(C1-3)alkoxy, carbomethoxymethyl, carbethoxymethyl, trifluoromethyl and carbamoyl, with the proviso that when R is hydrogen, R1 and R5 are methyl and R4 is carbethoxy, R2 and R3 cannot simultaneously represent hydrogen; And a salt thereof with a pharmaceutically acceptable acid. The compounds have anti-inflammatory and CNS-depressant utility. They are also useful as analgesics and antipyretics and display a very low degree of anti-ulcerogenic activity.