56465-64-6

Basic information

• Product Name: 1,3,2-Dioxaphosphorinane, 2-(dimethylamino)-5,5-dimethyl-
• Synonyms: 1,3,2-Dioxaphosphorinane, 2-(dimethylamino)-5,5-dimethyl-
• CAS NO: 56465-64-6
• Molecular Formula: C₇H₁₆NO₂P
• Molecular Weight: 177.18
• Mol File: 56465-64-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3,2-Dioxaphosphorinane, 2-(dimethylamino)-5,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,2-Dioxaphosphorinane, 2-(dimethylamino)-5,5-dimethyl-(56465-64-6)
• EPA Substance Registry System: 1,3,2-Dioxaphosphorinane, 2-(dimethylamino)-5,5-dimethyl-(56465-64-6)

Safety Data

• Hazardous Substances Data: 56465-64-6(Hazardous Substances Data)

Usage

Type of compound

Phosphorous-based

Usage

Reagent in organic synthesis reactions
Specifically used in the production of pharmaceuticals and agrochemicals

Physical state

Colorless to light yellow liquid

Flammability

Highly flammable

Safety precautions

Should be handled with caution

Additional uses

Solvent in some chemical processes
Applications in the field of materials science

Safety measures

Importance of using DMADMP in a controlled manner with appropriate safety measures in place
These properties and contents provide a comprehensive overview of DMADMP, highlighting its chemical structure, common name, applications, physical state, flammability, and the need for safety precautions during handling and use.

Upstream product

• 2428-06-0 2-chloro-5,5-dimethyl-[1,3,2]dioxaphosphinane 
• 124-40-3 dimethyl amine 

Downstream Products

• 15905-28-9 2-Thioxo-2-dimethylamino-5.5-dimethyl-1.3.2-dioxaphosphorinan 
• 737758-21-3 3',4',5,7-tetramethyldihydroquercetin-3-yl neopentylene phosphite 
• 3057-08-7 5,5-dimethyl-2-phenoxy-[1,3,2]dioxaphosphinane 
• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 

Relevant articles and documents

Hydrolysis of Cyclic Phosphites/Phosphoramidites and Its Inhibition-Reversible Cyclization of Acyclic Phosphonate Salts to Cyclic Phosphites

Hydrolysis of cyclic phosphites/phosphoramidites (OCH2- CRR′CH2O)PX [X = OPh (1), NMe2 (2)] in the presence of intentionally added water is effectively inhibited by using simple additives such as KF, K2CO3, Et3N, and molecular sieves. Among these, K2CO3 gave the best results. Cyclic H-phosphonates (OCH2CRR′CH2O)P(O)H (3), which are the tautomeric forms of the phosphites (OCH2CRR′CH 2O)P(OH), undergo facile hydrolysis in the presence of aqueous amines to give the acyclic phosphonate salts [H2NMe2] +[(HOCH2CRR′CH2O)P(O)-(H)(O-)] (4) that can be reverted back to 3 upon simple heating. Interestingly, competitive reactions of (OCH2CRR′CH2O)PX [X = Cl (I-III), NMe2 (2)] with phenol and water in the presence of K 2CO3 led only to the phenoxy derivatives and not to the hydrolysis products.