56472-03-8

Basic information

• Product Name: 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE
• Synonyms: 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE;2,4(or 6)-diamino-5-nitrosopyrimidine
• CAS NO: 56472-03-8
• Molecular Formula: C5H7N5O
• Molecular Weight: 153.14198
• Mol File: 56472-03-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE(56472-03-8)
• EPA Substance Registry System: 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE(56472-03-8)

Safety Data

• Hazardous Substances Data: 56472-03-8(Hazardous Substances Data)

Usage

General Description

2-4-6-Diamino-5-nitroso pyrimidine is a chemical compound with the molecular formula C4H4N6O2. It is a derivative of pyrimidine and is used in the synthesis of pharmaceuticals and agrochemicals. 2-4-6-DIAMINO-5-NITROSO PYRIMIDINE has been studied for its potential as an antimicrobial agent and has also shown promise in the treatment of certain types of cancer. Its nitroso group makes it useful in the development of nitrosamine-based chemical reactions, and its amino groups make it a versatile building block in organic synthesis. Overall, 2-4-6-diamino-5-nitroso pyrimidine has a range of potential applications in the fields of medicine and agriculture.

Upstream product

• 197165-78-9 2-methylpyrimidine-4,6-diamine 
• 1780-26-3 2,4-dichloro-2-methylpyrimidine 
• 40497-30-1 2-methyl-1H-pyrimidine-4,6-dione 
• 92972-45-7 isonitrosomalononitrile acetamidine salt 

Downstream Products

• 1445-08-5 2-methyl-6-aminopurine 
• 89364-18-1 4,5,6-triamino-2-methylpyrimidine 

Relevant articles and documents

Nucleosides part LXVI I[1]: Synthesis of 4-amino-7(8H) pteridinone-N8-nucleosides-structural analogs of adenosine

Various 4-amino-7(8H)pteridones (6, 12, 14, 15, 20, 22) have been glycosylated with 1-chloro-2'-deoxy-D-ribofuranose derivatives (25, 26) applying the new DBU-salt method to form the N8-2'-deoxy-D-ribofuranosides (27-36) which can be regarded as 2'-deoxyadenosine analogs. Analogously reacted the 2-N,N-dimethyl-amino-methyleneimino-7(8H)pteridones (43-48) to give preferentially the corresponding N8-ss-D-anomers (49-55). Ribosylation with 1-bromo-2,3,5-tri-O-benzoyl-a-D-ribofuranose (56) proceeded as well with 6, 12, 15, 45, and 46 to yield to N8-ss-D-ribofuranosides 57-61. Sugar deprotection led to the free N8-2'-deoxy-ss-D-ribofuranosides 37-42 and N8-ss-D-ribofurano-sides 62-65, respectively. Glycosylations via the silyl-method under Vorbruggen conditions led with 6, 12 and 15 to the same results, however, 4-amino-6-phenyl-7(8H)pteridone (14) reacted differently forming the N1-ss-D-ribofuranosides (71, 79) and the N1-2'-deoxy - and ss-D-ribofuranosides 73, 74, 77, 78. The assignments of the structures have been achieved by 1H-NMR- and UV-spectra. C,H,N-elemental analyses account for the composition.