565-65-1

Basic information

• Product Name: 1,1,2-TRIFLUORO-1,3-BUTADIENE
• Synonyms: 1,1,2-TRIFLUORO-1,3-BUTADIENE
• CAS NO: 565-65-1
• Molecular Formula: C₄H₃F₃
• Molecular Weight: 108.06
• Mol File: 565-65-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: -108 °C
• Boiling Point: 8°C
• Flash Point: °C
• Appearance: /
• Density: 1.089g/cm³
• CAS DataBase Reference: 1,1,2-TRIFLUORO-1,3-BUTADIENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,2-TRIFLUORO-1,3-BUTADIENE(565-65-1)
• EPA Substance Registry System: 1,1,2-TRIFLUORO-1,3-BUTADIENE(565-65-1)

Safety Data

• Hazard Codes: Xi
• Statements: 11
• Safety Statements: 9-16-33
• RIDADR: 3161
• Hazardous Substances Data: 565-65-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 3640, 1955 DOI: 10.1021/ja01618a063

Upstream product

• 3869-56-5 1,3-dibromo-1,1,2-trifluoro-butane 
• 401-52-5 4-iodo-1,1,2-trifluorobut-1-ene 
• 374-26-5 3,4-Dichlor-3,4,4-trifluor-buten-(1) 
• 374-25-4 4-bromo-3-chloro-3,4,4-trifluorobutene-1 
• 10493-44-4 1,1,2-trifluoro-4-bromobut-1-ene 
• 18599-22-9 4-bromo-3,3,4,4-tetrafluorobut-1-ene 
• 100-52-7 benzaldehyde 
• 116-14-3 polytetrafluoroethylene 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 3932-66-9 2,3,3-trifluoro-1-cyclobutene 
• 92818-42-3 1,2,2,5,6,6-hexafluorotricyclo<3.3.0.0^6,8>octane 
• 113894-43-2 (Z)-1,2-difluoro-1-phenyl-1,3-butadiene 
• 113894-38-5 (E)-1,2-difluoro-1-phenyl-1,3-butadiene 
• 113894-32-9 3-chloro-4-(phenylthio)-1,1,2-trifluoro-1-butene 

Relevant articles and documents

Preparation of trifluorovinyl compounds by lithium salt-promoted monoalkylation of tetrafluoroethene

Treatment of tetrafluoroethene (TFE) with diethylzinc in the presence of lithium iodide gave 1,1,2-trifluoro-1-butene in moderate yield. In the absence of lithium iodide, however, the nucleophilic addition of diethylzinc to TFE proceeded very slowly to afford ethyl 1,1,2,2-tetrafluorobutylzinc. The addition of lithium iodide to a solution of ethyl-1,1,2,2-tetrafluorobutylzinc resulted in a smooth transformation into 1,1,2-trifluoro-1-butene. In the presence of lithium chloride, the reaction of TFE with benzyl or allyl Grignard reagents afforded the corresponding monosubstituted products in good to excellent yields.

Fluorinated butene derivatives and methods for their preparation

New chemical reactions of 1,1,2-trifluoro-1,3-butadiene provide simple access to a series of new fluorinated alkene derivatives. These derivatives provide a simple, general methodology for the stereocontrolled preparation of 2-fluoro-2-alkenoate esters an