5651-83-2

Basic information

• Product Name: 3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE
• Synonyms: 3-methoxy-4-propargyloxy-benzaldehyde;ASISCHEM R29352;3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE;AKOS B028838;TIMTEC-BB SBB010822;3-Methoxy-4-(2-propynyloxy)benzaldehyde;3-methoxy-4-(prop-2-yn-1-yloxy)benzaldehyde;3-methoxy-4-prop-2-ynoxybenzaldehyde
• CAS NO: 5651-83-2
• Molecular Formula: C₁₁H₁₀O₃
• Molecular Weight: 190.2
• Mol File: 5651-83-2.mol
• Article Data: 73

Chemical Properties

• Boiling Point: 325.2°C at 760 mmHg
• Flash Point: 141.6°C
• Appearance: /
• Density: 1.146g/cm³
• Vapor Pressure: 0.000233mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE(5651-83-2)
• EPA Substance Registry System: 3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE(5651-83-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36-43
• Safety Statements: 26-36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 5651-83-2(Hazardous Substances Data)

Usage

General Description

3-Methoxy-4-prop-2-ynyloxy-benzaldehyde is a chemical compound with the molecular formula C11H10O3. It is a yellowish liquid with a strong odor, often used in the fragrance and flavor industry. 3-METHOXY-4-PROP-2-YNYLOXY-BENZALDEHYDE is commonly used as a flavoring agent in various food and beverage products, as well as a component in perfumes and personal care products. It is also utilized in organic synthesis and pharmaceutical research. 3-Methoxy-4-prop-2-ynyloxy-benzaldehyde is known for its aromatic and sweet fragrance, making it a popular choice for enhancing the scent and taste of consumer goods.

InChI:InChI=1/C11H10O3/c1-3-6-14-10-5-4-9(8-12)7-11(10)13-2/h1,4-5,7-8H,6H2,2H3

Upstream product

• 121-33-5 vanillin 
• 106-96-7 propargyl bromide 
• 74-88-4 methyl iodide 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 77-78-1 dimethyl sulfate 
• 65881-41-6 N-Acetylpropargylamine 
• 405-05-0 3-fluoro-4-hydroxybenzaldehyde 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 139386-35-9 5-Formyl-7-methoxy-2-methylbenzofuran 
• 146607-43-4 3-methoxy-4-(2-propynyloxy)benzaldehyde diethyl acetal 
• 139386-33-7 5-hydroxy-4-formyl-7-methoxy-2-methylbenzofuran 
• 146607-45-6 5-benzyloxy-7-methoxy-2-methylbenzofuran 
• 146607-46-7 5-benzyloxy-4-formyl-7-methoxy-2-methylbenzofuran 
• 1042423-00-6 C₁₇H₁₄O₃ 
• 1198769-75-3 4-(3-iodoprop-2-ynyloxy)-3-methoxybenzaldehyde 
• 1261145-43-0 3-(3-methoxy-4-prop-2-ynyloxy-phenyl)-1-(2,3,4-trimethoxy-phenyl)-propenone 
• 1261145-42-9 1-(2,4-dimethoxy-phenyl)-3-(3-methoxy-4-prop-2-ynyloxy-phenyl)-propenone 
• 1261145-41-8 1-(4-methoxy-phenyl)-3-(3-methoxy-4-prop-2-ynyloxy-phenyl)-propenone 
• 1259022-95-1 (E)-2-[3-(3-methoxy-4-(propargyloxy)phenyl)-1-oxo-2-propenyl]benzoic acid 
• 1261145-76-9 4-[(1-(7-chloro-quinolin-4-yl)-1H-[1,2,3]triazol-4-yl)methoxy]-3-methoxy-benzaldehyde 
• 1261145-34-9 4-(3-methoxy-4-prop-2-ynyloxy-phenyl)-but-3-en-2-one 
• 1295536-76-3 (E)-2-(3-methoxy-4-propargyloxystyryl)-4H-benzo[d][1,3]oxazin-4-one 

Relevant articles and documents

"Clicked" bivalent ligands containing curcumin and cholesterol as multifunctional Aβ oligomerization inhibitors: Design, synthesis, and biological characterization

In our effort to develop multifunctional compounds that cotarget beta-amyloid oligomers (AβOs), cell membrane/lipid rafts (CM/LR), and oxidative stress, a series of bivalent multifunctional Aβ oligomerization inhibitors (BMAOIs) containing cholesterol and curcumin were designed, synthesized, and biologically characterized as potential treatments for Alzheimer's disease (AD). The in vitro assay results established that the length of spacer that links cholesterol and curcumin and the attaching position of the spacer on curcumin are important structural determinants for their biological activities. Among the BMAOIs tested, 14 with a 21-atom-spacer was identified to localize to the CM/LR of human neuroblastoma MC65 cells, to inhibit the formation of AβOs in MC65 cells, to protect cells from AβOs-induced cytotoxicity, and to retain antioxidant properties of curcumin. Furthermore, 14 was confirmed to have the potential to cross the blood-brain barrier (BBB) as demonstrated in a Caco-2 cell model. Collectively, these results strongly encourage further optimization of 14 as a new hit to develop more potent BMAOIs.

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A Facile Eco-Friendly One-Pot Five-Component Synthesis of Novel 1,2,3-Triazole-Linked Pentasubstituted 1,4-Dihydropyridines and their Biological and Photophysical Studies

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Design and synthesis of 1,4-disubstituted 1,2,3-triazoles: Biological evaluation, in silico molecular docking and ADME screening

In this study, propargyl compounds were synthesized from 4-hydroxybenzaldehyde and 3?methoxy-4-hydroxybenzaldehyde (2a-2b). As a result of click reactions of synthesized propargyl compounds (2a-b) with organic azides (4a-4e), carbonyl compounds (5a-5 h) h

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In the present work, new benzimidazole linked 1,2,3-triazole hybrids have been synthesized and screened for antiproliferative and EGFR kinase inhibitory activities.The structures of these hybrids were elucidated using IR, NMR, mass spectrometry and elemen

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