5652-68-6Relevant articles and documents
Synthesis and anticonvulsant activity of ethyl 2,2-dimethyl-1-(2- substitutedhydrazinecarboxamido) cyclopropanecarboxylate derivatives
Zhong, Min,Zhang, Yongmin,He, Xianran
, p. 234 - 241 (2014)
In this study on the development of new anticonvulsants, fourteen ethyl 2,2-dimethyl-1-(2-substitutedhydrazinecarboxamido) cyclopropanecarboxylate derivatives were synthesized and tested for anticonvulsant activity using the maximal electroshock, subcutan
Three partners of a one pot palladium-mediated synthesis of various tetrahydrofurans
Cavicchioli,Sixdenier,Derrey,Bouyssi,Balme
, p. 1763 - 1766 (1997)
Substituted furans are obtained in a one step procedure from addition of allylic alkoxides to Michael accepters followed by a palladium catalysed cyclisation involving iodo-aryl compounds.
Facile synthesis of β-azidocyclopropanecarboxylates by MIRC reaction
Su, Jiangtao,Qiu, Guofu,Liang, Shucai,Hu, Xianming
, p. 1427 - 1433 (2005)
Two β-azidocyclopropanecarboxylates are readily synthesized from β-bromoalkyliden malonates via a Michael-initiated ring closure (MIRC) reaction in moderate yields, which are regarded as precursors of β-aminocyclopropanecarboxylic acids. Copyright Taylor & Francis, Inc.
Metal-Organic Framework Anchored with a Lewis Pair as a New Paradigm for Catalysis
Niu, Zheng,Bhagya Gunatilleke, Wilarachchige D.C.,Sun, Qi,Lan, Pui Ching,Perman, Jason,Ma, Jian-Gong,Cheng, Yuchuan,Aguila, Briana,Ma, Shengqian
supporting information, p. 2587 - 2599 (2018/12/02)
Lewis pair (LP) chemistry has shown broad applications in the catalysis field. However, one significant challenge has been recognized as the instability for most homogeneous LP catalysts upon recycling, thus inevitably leading to dramatic loss in catalytic activity. Additionally, current heterogeneous LP catalysts suffer from low surface area, which largely limits their catalytic efficiency, thereby restricting their potential applications. In this work, we report the successful introduction of LPs, classical and frustrated, into a metal-organic framework (MOF) that features high surface and ordered pore structure via a stepwise anchoring strategy. Not only can the LP be stabilized by the strong coordination interaction between the LP and MOF, but the resultant MOF-LP also demonstrates excellent catalysis performance with interesting size and steric selectivity. Given the broad applicability of LPs, our work therefore paves a way for advancing MOF-LP as a new paradigm for catalysis. Lewis pairs (LPs), classical and frustrated, are excellent prospects in catalysis, organic syntheses, biology, and material sciences. However, the instability of most LP catalysts leads to a dramatic loss in activities, thereby largely restricting their industrial applications. As robust porous materials, metal-organic frameworks (MOFs) offer a platform to stabilize homogeneous catalysts. Here, we show a strategy that grafts the LP catalyst on the MOF to minimize loss of LPs during catalysis and recycling. Our work reveals the enormous potential of MOFs as an appealing paradigm for the construction of efficient heterogeneous catalysts with interesting steric and size selectivity worthy of exploration. In addition, the strategies for anchoring a LP into a MOF as contributed herein can be readily applied for the task-specific design of functional catalysis materials for various applications. Lewis pairs (LPs), classical and frustrated, have been successfully introduced into and stabilized in a metal-organic framework (MOF). Benefiting from the robust framework and tunable porous structure of MOFs, the resultant MOF-LP demonstrates not only great recyclability but also excellent performance in the catalytic reduction of imines and hydrogenation of alkenes. The combination of LP and MOF therefore lays a foundation for developing a MOF-LP as a new paradigm for catalysis, particularly heterogeneous catalysis.
