56521-73-4

Basic information

• Product Name: 2-ethoxyethyl bromoacetate
• Synonyms: 2-ethoxyethyl bromoacetate;Ethyleneglycol monoethyl ether bromoacetate;2-Bromoacetic acid 2-ethoxyethyl ester;Einecs 260-240-9
• CAS NO: 56521-73-4
• Molecular Formula: C₆H₁₁BrO₃
• Molecular Weight: 211.05374
• EINECS: 260-240-9
• Mol File: 56521-73-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 232.6 °C at 760 mmHg
• Flash Point: 94.5 °C
• Appearance: /
• Density: 1.401 g/cm³
• Vapor Pressure: 0.0584mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 2-ethoxyethyl bromoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxyethyl bromoacetate(56521-73-4)
• EPA Substance Registry System: 2-ethoxyethyl bromoacetate(56521-73-4)

Safety Data

• Hazardous Substances Data: 56521-73-4(Hazardous Substances Data)

Usage

General Description

2-ethoxyethyl bromoacetate, also known as ethyl 2-bromoacetoxyethyl ether, is an organic compound with the formula C6H11BrO3. It is a colorless liquid with a fruity odor commonly used in the production of pharmaceuticals and agrochemicals. It is a versatile reagent for the synthesis of various compounds due to its ability to undergo nucleophilic substitution reactions and esterification. The compound is considered to be a hazardous chemical due to its corrosive and toxic nature, and proper safety precautions should be taken when handling and storing it.

InChI:InChI=1/C6H11BrO3/c1-2-9-3-4-10-6(8)5-7/h2-5H2,1H3

Upstream product

• 110-80-5 2-ethoxy-ethanol 
• 598-21-0 2-Bromoacetyl bromide 

Relevant articles and documents

Tandem ionic liquid antimicrobial toxicity and asymmetric catalysis study: Carbonyl-ene reactions with trifluoropyruvate

The asymmetric carbonyl-ene reaction of trifluoropyruvate with five alkenes catalysed by [Pd{(R)-BINAP}](SbF6)2 were carried out in good yields and enantioselectivities (up to 96% yield and 96% ee) in low antimicrobial toxicity C2-substituted imidazolium ionic liquids (ILs). Toxicity data was included in the selection criteria for reaction optimisation after a preliminary IL screen. The Pd(ii) catalyst immobilised in an IL was recycled and reused up to 7 times without decrease of either yield or ee. One IL prepared, which was determined to be of high antimicrobial toxicity was assigned a low priority for future applications.

Selective hydrogenation of trans-cinnamaldehyde and hydrogenolysis-free hydrogenation of benzyl cinnamate in imidazolium ILs

trans-Cinnamaldehyde is selectively hydrogenated to hydrocinnamaldehyde using a commercially available palladium catalyst in novel imidazolium ILs. The selective hydrogenation extends to benzyl cinnamate, in which the ester is protected from hydrogenolysis under similar conditions.