5653-12-3

Basic information

• Product Name: 2-(3,4-dihydroquinolin-1(2H)-yl)-1-phenylethanone
• CAS NO: 5653-12-3
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.323
• Mol File: 5653-12-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 428.5°C at 760 mmHg
• Flash Point: 171.5°C
• Density: 1.12g/cm³
• Vapor Pressure: 1.51E-07mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: 2-(3,4-dihydroquinolin-1(2H)-yl)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dihydroquinolin-1(2H)-yl)-1-phenylethanone(5653-12-3)
• EPA Substance Registry System: 2-(3,4-dihydroquinolin-1(2H)-yl)-1-phenylethanone(5653-12-3)

Safety Data

• Hazardous Substances Data: 5653-12-3(Hazardous Substances Data)

Usage

Type of compound

ketone

Structure

A derivative of quinoline with a phenyl group attached to the carbonyl carbon

Biological activity

Potential inhibitor of the enzyme cholinesterase

Function

Involved in the breakdown of the neurotransmitter acetylcholine

Potential use

Treatment of neurodegenerative diseases such as Alzheimer's

Note

Further research is needed to fully understand its biological effects and potential applications.

Upstream product

• 70-11-1 α-bromoacetophenone 
• 767-92-0 decahydroquinoline 
• 635-46-1 1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 88920-05-2 2,2a,3,4-tetrahydro-2-phenyl-1H-azeto<1,2-a>quinolin-2-ol 
• 98-86-2 acetophenone 

Relevant articles and documents

Synthesis of chiral alcohols by asymmetric reductions of various ketones including α-aminophenones

LiAlH4 previously treated with 2.5 equiv. of (S)-(+) or (R)-(-)-2-(2-isoindolinyl)butan-1-ol 1 reduced the six α-aminophenones 4-9 into the corresponding optically active β-aminoalcohols 10-15 whose ee's were in the range of 40-97% after chroma