56541-14-1

Basic information

• Product Name: N-CYCLOPROPYLTHIOUREA
• Synonyms: 1-Cyclopropylthiourea;1-Cyclopropyl-2-thiourea
• CAS NO: 56541-14-1
• Molecular Formula: C₄H₈N₂S
• Molecular Weight: 116.18
• Mol File: 56541-14-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 201.9±23.0℃ (760 Torr)
• Flash Point: 75.9±22.6℃
• Appearance: /
• Density: 1.24±0.1 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.3mmHg at 25°C
• Refractive Index: 1.621
• PKA: 14.68±0.20(Predicted)
• CAS DataBase Reference: N-CYCLOPROPYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-CYCLOPROPYLTHIOUREA(56541-14-1)
• EPA Substance Registry System: N-CYCLOPROPYLTHIOUREA(56541-14-1)

Safety Data

• Hazardous Substances Data: 56541-14-1(Hazardous Substances Data)

Usage

General Description

N-CYCLOPROPYLTHIOUREA is a chemical compound with the molecular formula C4H8N2S. It is a cyclic organic compound that contains a thiourea functional group, which consists of a sulfur atom bonded to a nitrogen atom. N-CYCLOPROPYLTHIOUREA is used in various chemical and pharmaceutical processes as a building block to synthesize new compounds for research and drug development. It is also utilized as an intermediate in the production of pesticides, herbicides, and fungicides. Additionally, it has potential applications in the field of organic synthesis and materials science due to its reactivity and unique chemical properties.

InChI:InChI=1/C4H8N2S/c5-4(7)6-3-1-2-3/h3H,1-2H2,(H3,5,6,7)

Upstream product

• 56541-16-3 N-cyclopropyl-N'-benzoylthiourea 
• 56601-42-4 cyclopropyl isothiocyanate 
• 1158178-29-0 triethylammonium cyclopropyldithiocarbamate 
• 333-20-0 potassium thioacyanate 
• 765-30-0 Cyclopropylamine 

Downstream Products

• 860344-66-7 4-(2-cyclopropylamino-thiazol-4-yl)-benzoic acid 
• 1126431-34-2 4-[4-chloro-3-(methyloxy)phenyl]-5-(2-chloro-4-pyrimidinyl)-N-cyclopropyl-1,3-thiazol-2-amine 
• 1126430-48-5 4-[3,5-bis(methyloxy)phenyl]-5-(2-chloro-4-pyrimidinyl)-N-cyclopropyl-1,3-thiazol-2-amine 
• 1160623-50-6 N-(3-(5-(2-chloro-4-pyrimidinyl)-2-(cyclopropylamino)-1,3-thiazol-4-yl)phenyl)-2,6-difluorobenzamide 
• 1229383-84-9 4-(2-bromophenyl)-N-cyclopropylthiazol-2-amine 

Relevant articles and documents

GLYCOSIDASE INHIBITORS

Compounds of formula (I) wherein X1, X2, W, R1 to R5, L and m have the meaning according to the claims, are glucosidase inhibitors, and can be employed, inter alia, for the treatment of Alzheimer's disease.

2-amino-1,3-thiazoles suppressed lipopolysaccharide-induced il-β and TNF-α

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An efficient synthesis of cyanamide from amine promoted by a hypervalent iodine(III) reagent

In a one-pot strategy we have achieved an efficient method for the synthesis of organic cyanamides starting from dithiocarbamic acid salts/amines. In this strategy the in situ generated alkyl or aryl isothiocyanates, obtained by the desulfurization of dithiocarbamic acid salts with diacetoxyiodobenzene (DIB) react with aqueous ammonia forming alkyl or aryl thiourea which on subsequent oxidative desulfurization with DIB led to the formation of corresponding cyanamide in good yields. Mild reaction conditions, shorter reaction time, an environmentally benign protocol, and easy isolation of the desired product make the present methodology a suitable alternative for the preparation of various organic cyanamides.