5657-17-0

Basic information

• Product Name: Ethylenediamine-N,N'-diacetic acid
• Synonyms: ((2-[(Carboxymethyl)amino]ethyl)amino)acetic acid;Acetic acid, 2,2'-(1,2-ethanediyldiimino)bis-;Ethylenediaminediacetic acid;Ethylenediiminodiacetic acid;Glycine, N,N'-ethylenedi-;n,n’-1,2-ethanediylbis-glycin;N,N'-Ethylenediaminediacetic Acid;N,N'-ETHYLENEDIGLYCINE
• CAS NO: 5657-17-0
• Molecular Formula: C₆H₁₂N₂O₄
• Molecular Weight: 176.17
• EINECS: 227-105-6
• Mol File: 5657-17-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 224 °C (dec.)(lit.)
• Boiling Point: 307.77°C (rough estimate)
• Appearance: /
• Density: 1.3600 (rough estimate)
• Vapor Pressure: 0Pa at 20℃
• Refractive Index: 1.4431 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: pK1:6.42;pK2:9.46 (25°C)
• Water Solubility: Soluble in warm water.
• BRN: 1778355
• CAS DataBase Reference: Ethylenediamine-N,N'-diacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Ethylenediamine-N,N'-diacetic acid(5657-17-0)
• EPA Substance Registry System: Ethylenediamine-N,N'-diacetic acid(5657-17-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 5657-17-0(Hazardous Substances Data)

Usage

Chemical Properties

white powder

Uses

Different sources of media describe the Uses of 5657-17-0 differently. You can refer to the following data:
1. Ethylenediamine-N,N'-diacetic acid is acts as a chelating agent, used as a haemostatic.
2. Ethylenediamine-N,N′-diacetic acid (EDDA) is a chelating agent that can be used to synthesize:Binary and ternary copper(II) complexes with potent proteasome inhibitory properties.Pd(EDDA) complexes which can coordinate with amino acids, peptides, or DNA units.

Definition

ChEBI: An ethylenediamine derivative in which two of the four amine protons of ethylenediamine are replaced by carboxymethyl groups.

Flammability and Explosibility

Notclassified

Purification Methods

Crystallise EDDA from H2O. [Beilstein 4 IV 2446.]

Upstream product

• 50-00-0 formaldehyd 
• 74-90-8 hydrogen cyanide 
• 107-15-3 ethylenediamine 
• 143-33-9 sodium cyanide 
• 60-00-4 ethylenediaminetetraacetic acid 
• 79-11-8 chloroacetic acid 

Downstream Products

• 90936-71-3 N,N'-di(5-sodiumsulfonate-2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid 
• 35369-53-0 N,N'-ethylenebis[N-(o-hydroxybenzyl)glycine] 
• 102212-15-7 N,N'-bis(benzyloxycarbonyl)ethylenediamine-N,N'-diacetic acid 
• 36129-26-7 N,N'-di(3,5-dimethyl-2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid 
• 103292-71-3 (3-Carboxymethyl-imidazolidin-1-yl)-acetic acid 
• 24860-46-6 2-(2-oxopiperazino)acetic acid 

Relevant articles and documents

Bioassay studies of metal(II) complexes of 2,2′-(ethane-1,2- diyldiimino)diacetic acid

Ni(II), Cu(II) and Zn(II) coordination compounds with modified diammine 2,2′-(ethane-1,2-diyldiimino)diacetic acid (EDDA) were prepared and characterized. Coordination complexes of the EDDA were characterized by physical measurements including elemental analysis, IR, UV-Visible, magnetic susceptibilities and conductance measurements. The complexes were screened against four pathogenic bacteria like Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus and their concentrations for maximum inhibition zones were obtained.

Kinetics and Mechanism of the Oxidation of Iminodiacetate, Nitrilotriacetate and Ethylenediaminetetraacetate by trans-Cyclohexane-1,2-diamine-N,N,N',N'-tetraacetatomanganate(III) in Aqueous Media

Kinetic studies of the oxidation of iminodiacetate (ida), nitrilotriacetate (nta) and ethylenediaminetetraacetate (edta) by trans-cyclohexane-1,2-diamine-N,N,N',N'-tetraacetatomanganate(III), III(cdta)>(1-), have been made in aqueous solution in the range pH 3.0-10.0 with varying reductant concentrations at constant ionic strength, I = 0.50 mol dm-3 (NaClO4), and temperature, 30 deg C.All the reactions are first order in complex and reductant concentration, and follow the general rate law -dIII>/dt = kobsIII> = (kd + ks)III>, where kd denotes the autodecomposition rate of the complex, ks the electron-transfer rate and R is the reductant irrespective of the nature and type of the reacting species.The complex III(cdta)>(1-) showed an interesting behaviour in acidic and alkaline media.For ida oxidation both the aqua- and hydroxo-forms of the complex are reactive and an inner-sphere mechanism has been proposed.However, for nta and edta oxidations, the aqua form is the sole reacting species and an outer-sphere mechanism has been proposed.The rate parameters and proton equilibrium constant of the complex and reductants were obtained by fitting of the experimental data by appropriate rate equations using computer-fit programs.Thus the reactivities of all the species of the polycarboxylates available in the reaction solutions have been evaluated individulally.The reactivity orders are Hida(1-) ida(2-), H2nta(1-) Hnta(2-) nta(3-) and H3edta(1-) H2edta(2-) Hedta(3-) edta(4-).