5663-03-6

Basic information

• Product Name: 1-(TRIMETHYLSILYLMETHYL)UREA
• Synonyms: 1-(TRIMETHYLSILYLMETHYL)UREA;N-(trimethylsilylmethyl)urea;Einecs 227-117-1
• CAS NO: 5663-03-6
• Molecular Formula: C₅H₁₄N₂OSi
• Molecular Weight: 146.26
• EINECS: 227-117-1
• Product Categories: Carbonyl Compounds;Organic Building Blocks;Ureas
• Mol File: 5663-03-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 115-117 °C(lit.)
• Boiling Point: 185.7°Cat760mmHg
• Flash Point: 66.1°C
• Appearance: /
• Density: 0.935g/cm³
• Vapor Pressure: 0.688mmHg at 25°C
• Refractive Index: 1.438
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(TRIMETHYLSILYLMETHYL)UREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TRIMETHYLSILYLMETHYL)UREA(5663-03-6)
• EPA Substance Registry System: 1-(TRIMETHYLSILYLMETHYL)UREA(5663-03-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 5663-03-6(Hazardous Substances Data)

Usage

General Description

1-(Trimethylsilylmethyl)urea is a chemical compound that belongs to the class of urea derivatives. It is a white solid and is commonly used as a reagent in organic synthesis. 1-(TRIMETHYLSILYLMETHYL)UREA is known for its ability to act as a powerful and selective reagent for the protection of carbonyl groups in organic molecules. Additionally, it is also used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 1-(Trimethylsilylmethyl)urea is an important chemical in organic chemistry and has a wide range of applications in the field of chemical synthesis and drug development.

InChI:InChI=1/C5H14N2OSi/c1-9(2,3)4-7-5(6)8/h4H2,1-3H3,(H3,6,7,8)

Upstream product

• 18166-02-4 N-trimethylsilylmethylamine 
• 556-89-8 nitrourea 
• 14283-35-3 (trimethylsilyl)methyl isocyanate 
• 57-13-6 urea 
• 2344-80-1 Chloromethyltrimethylsilane 
• 20160-71-8 N-Trimethylsilylmethyl-N'.N'-diphenyl-harnstoff 

Downstream Products

• 39482-21-8 N-trimethylsilylmethyl-N-nitrosourea 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 591-63-9 n-butyl crotonate 
• 1372786-08-7 1-benzyl-3-((trimethylsilyl)methyl)urea 

Relevant articles and documents

New methods and reagents in organic synthesis. 17. Trimethylsilyldiazomethane (TMSCHN2) as a stable and safe substitute for hazardous diazomethane. Its application to the Arndt-Eistert synthesis

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