56674-34-1

Basic information

• Product Name: S-(2-chloroethyl)cysteine
• Synonyms: cysteine, S-(2-chloroethyl)-; S-(2-Chloroethyl)cysteine
• CAS NO: 56674-34-1
• Molecular Formula: C₅H₁₀ClNO₂S
• Molecular Weight: 183.6564
• Mol File: 56674-34-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 343.8°C at 760 mmHg
• Flash Point: 161.7°C
• Density: 1.359g/cm³
• Vapor Pressure: 1.23E-05mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: S-(2-chloroethyl)cysteine(CAS DataBase Reference)
• NIST Chemistry Reference: S-(2-chloroethyl)cysteine(56674-34-1)
• EPA Substance Registry System: S-(2-chloroethyl)cysteine(56674-34-1)

Safety Data

• Hazardous Substances Data: 56674-34-1(Hazardous Substances Data)

Upstream product

• 85955-36-8 (S)-2-amino-3-<(2-hydroxyethyl)sulfanyl>propanoic acid 
• 6367-98-2 (-)-(2R)-2-amino-3-(2-hydroxyethylsulfanyl)propanoic acid 
• 97170-10-0 S-hydroxyethylcysteine 
• 75-21-8 oxirane 
• 921-01-7 rac-cysteine 

Downstream Products

• 65527-54-0 2-(R)-thiomorpholine carboxylic acid hydrochloride 
• 872424-97-0 2-amino-3-(2-chloro-ethylsulfanyl)-propionic acid methyl ester hydrochloride 
• 220605-36-7 (3R)-4-(toluene-4-sulfonyl)thiomorpholine-3-carboxylic acid 
• 73401-53-3 L-tetrahydro-2H-1,4-thiazine-3-carboxylic acid 

Relevant articles and documents

Synthesis of Optically Active 1,4-Thiazane-3-carboxylic Acid via Optical Resolution by Preferential Crystallization of (RS)2-Amino-3-[(2-chloroethyl)sulfanyl]propanoic Acid Hydrochloride

Optically active 1,4-thiazane-3-carboxylic acid [TCA] was synthesized from cysteine via optical resolution by preferential crystallization. The intermediate (RS)-2-amino-3-[(2-chloroethyl)sulfanyl]propanoic acid hydrochloride [(RS)-ACS-HCl] was found to exist as a conglomerate based on its melting point, solubility and IR spectrum. (RS)-ACS·HCl was optically resolved by preferential crystallization to yield (R)- and (S)-ACS·HCl. (R)- and (S)-ACS·HCl thus obtained were recrystallized from a mixture of hydrochloric acid and 2-propanol, taking account of the solubility of (RS)-ACS·HCl, efficiently yielding both enantiomers in optically pure forms. (R)- and (S)-TCA were then respectively synthesized by the cyclization of (R)- and (S)-ACS·HCI in ethanol in the presence of triethylamine.

Thiazine amide derivative thereof in the preparation of medicaments for preventing neurodegenerative diseases, the use of the

The invention relates to a compound shown as the formula I, pharmaceutically acceptable salts of the compound, and/ or solvates and/ or hydrates of the compound. The invention also relates to a preparation method of the compound, a medicinal composition c

THIAZINE AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

The present invention relates to a thiazine amide derivative and a pharmaceutical use thereof, and particularly to a compound of formula I (in the formula, variables are as described in the specification), a pharmaceutically acceptable salt, solvate or hy