56674-69-2

Basic information

• Product Name: 2-METHOXYBUTANOIC ACID
• Synonyms: 2-METHOXYBUTANOIC ACID;2-methoxybutanoic acid(SALTDATA: FREE);2-methoxybutyric acid
• CAS NO: 56674-69-2
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 118.13
• Mol File: 56674-69-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 215℃
• Flash Point: 90℃
• Appearance: /
• Density: 1.050
• Vapor Pressure: 0.06mmHg at 25°C
• Refractive Index: 1.42527
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-METHOXYBUTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYBUTANOIC ACID(56674-69-2)
• EPA Substance Registry System: 2-METHOXYBUTANOIC ACID(56674-69-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 56674-69-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 58, p. 2784, 1980 DOI: 10.1139/v80-445

InChI:InChI=1/C5H10O3/c1-3-4(8-2)5(6)7/h4H,3H2,1-2H3,(H,6,7)

Upstream product

• 15467-25-1 2-methoxy-1-butanol 
• 88126-31-2 α-methoxycrotonic acid 
• 124-41-4 sodium methylate 
• 533-68-6 2-bromobutyric acid ethyl ester 
• 67-56-1 methanol 
• 6111-61-1 ethyl(trichloromethyl)carbinol 
• 17356-08-0 thiourea 
• 18231-00-0 2-(R)-2-Methoxybut-3-en-1-ol 
• 29674-47-3 methyl 2-hydroxybutyrate 
• 74-88-4 methyl iodide 

Downstream Products

• 1415141-57-9 3-(4-((3-fluorophenyl)ethynyl)phenyl)-5-(1-methoxypropyl)-1,2,4-oxadiazole 

Relevant articles and documents

Stereodivergence in the Ireland-Claisen Rearrangement of α-Alkoxy Esters

A systematic investigation into the Ireland-Claisen rearrangement of α-alkoxy esters is reported. In all cases, the use of KN(SiMe3)2 in toluene gave rearrangement products corresponding to a Z-enolate intermediate with excellent diastereoselectivity, presumably because of chelation control. On the other hand, chelation-controlled enolate formation could be overcome for most substrates through the use of lithium diisopropylamide (LDA) in tetrahydrofuran (THF).