5670-51-9

Basic information

• Product Name: 1-Methyl-2-oxocyclohexanecarbonitrile
• Synonyms: 1-Methyl-2-oxocyclohexanecarbonitrile
• CAS NO: 5670-51-9
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.17904
• Mol File: 5670-51-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-2-oxocyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-oxocyclohexanecarbonitrile(5670-51-9)
• EPA Substance Registry System: 1-Methyl-2-oxocyclohexanecarbonitrile(5670-51-9)

Safety Data

• Hazardous Substances Data: 5670-51-9(Hazardous Substances Data)

Usage

Type of compound

Cyclic ketone

Presence of functional groups

Nitrile group

Versatility in organic synthesis

Acts as a valuable intermediate

Common uses

Preparation of pharmaceuticals and agrochemicals

Chemical reactivity

Ability to undergo various chemical reactions and form diverse functional groups

Applications

Production of fine chemicals, dyes, and specialty chemicals

Potential use in materials science

Synthesis of complex organic molecules

Upstream product

• 4513-77-3 2-cyanocyclohexanone 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 646-20-8 pimelonitrile 
• 15595-71-8 2-aminocyclohex-1-enecarbonitrile 
• 822-87-7 2-Chlorocyclohexanone 
• 152297-24-0 (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-methyl-cyclohexanecarbonitrile 
• 406909-97-5 (1R,2S)-1-methyl-2-hydroxy-1-cyclohexanecarbonitrile 

Downstream Products

• 50744-44-0 (Z)-6-Cyano-5-heptenal 
• 50744-43-9 (E)-6-Cyano-5-heptenal 
• 1206-21-9 2-benzyl-2-methyl-cyclohexanone 
• 16178-87-3 2-methyl-2-allylcyclohexanone 
• 66984-23-4 2-hydroxy-1-methylcyclohexanecarbonitrile 
• 406909-98-6 (1S,2S)-1-methyl-2-hydroxy-1-cyclohexanecarbonitrile 
• 406909-97-5 (1R,2S)-1-methyl-2-hydroxy-1-cyclohexanecarbonitrile 
• 66984-23-4 (+/-)-(1R,2S)-1-methyl-2-hydroxy-1-cyclohexanecarbonitrile 
• 1032593-02-4 C₁₄H₁₅NS 

Relevant articles and documents

Synthesis and Enzymatic Kinetic Resolution of α,α -Disubstituted Cyclic Hydroxy Nitriles

Herein, we describe the diastereoselective synthesis of five- and six-membered α,α-disubstituted cyclic β-hydroxy nitriles and their resolution via enzymatic transesterification. By this method, all possible stereoisomers were obtained in enantiopure form and high yield.

Lithium naphthalenide induced reductive alkylation of α-cyano ketones. A general method for regiocontrol of α,α-dialkylation of ketones

An efficient general method for the consecutive introduction of two alkyl groups to the α carbon of a ketone carbonyl has been developed, making use of the lithium naphthalenide induced reductive alkylation of an α-cyano ketone system as a key operation.