56719-08-5

Basic information

• Product Name: 3-(2,5-dichlorophenyl)-3-oxopropanenitrile
• Synonyms: 3-(2,5-dichlorophenyl)-3-oxopropanenitrile
• CAS NO: 56719-08-5
• Molecular Formula: C₉H₅Cl₂NO
• Molecular Weight: 214.05
• Mol File: 56719-08-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 346.2°C at 760 mmHg
• Flash Point: 163.2°C
• Appearance: /
• Density: 1.383g/cm³
• Vapor Pressure: 5.85E-05mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 3-(2,5-dichlorophenyl)-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,5-dichlorophenyl)-3-oxopropanenitrile(56719-08-5)
• EPA Substance Registry System: 3-(2,5-dichlorophenyl)-3-oxopropanenitrile(56719-08-5)

Safety Data

• Hazardous Substances Data: 56719-08-5(Hazardous Substances Data)

Usage

General Description

3-(2,5-dichlorophenyl)-3-oxopropanenitrile is a chemical compound with a molecular formula C9H4Cl2NO. It is a nitrile compound with a phenyl group substituted at the 3-position and two chlorine atoms at the 2 and 5 positions. 3-(2,5-dichlorophenyl)-3-oxopropanenitrile is commonly used in organic synthesis and is known to have pesticidal and herbicidal properties. Additionally, it is also used as a building block in the production of pharmaceuticals, agrochemicals, and dyes. It is important to handle this compound with care as it can be toxic and harmful if not used properly.

InChI:InChI=1/C9H5Cl2NO/c10-6-1-2-8(11)7(5-6)9(13)3-4-12/h1-2,5H,3H2

Upstream product

• 4571-25-9 2-bromo-1-(2,5-dichlorophenyl)ethanone 
• 143-33-9 sodium cyanide 
• 2476-37-1 2,5-dichloroacetophenone 
• 35112-27-7 ethyl 2,5-dichlorobenzoate 
• 75-05-8 acetonitrile 

Downstream Products

• 934340-24-6 C₁₂H₉Cl₂NO₃ 
• 934340-37-1 C₁₄H₁₁Cl₂NO₄ 
• 934340-40-6 C₁₅H₁₃Cl₂NO₄ 
• 934340-33-7 C₁₆H₁₅Cl₂NO₃ 
• 1217089-16-1 C₉H₇Cl₂N₃ 

Relevant articles and documents

Design, synthesis, and evaluation of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines as novel PDE-4 inhibitors

Described herein is design, synthesis, and biological evaluation of novel series of 2-aryl-7-(3′,4′-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines acting as inhibitors of type 4 phosphodiesterase (PDE4) which is known as a good target for the treatment of asthma and COPD. For this purpose, structure optimization was conducted with the aid of structure-based drug design using the known X-ray crystallography. Also, biological effects of these compounds on the target enzyme were evaluated by using in vitro assays, leading to the potent and selective PDE-4 inhibitor (IC50 10 nM).

Cis-2-benzoyl-3-hydroxy-2-alkenonitriles as anti-inflammatory agents

This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-benozyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.