568-80-9

Basic information

• Product Name: Galloflavin
• Synonyms: Galloflavin;3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione;NSC 107022;6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione;3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione,NSC 107022
• CAS NO: 568-80-9
• Molecular Formula: C12H6O8
• Molecular Weight: 278.17124
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 568-80-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 159.8°Cat760mmHg
• Flash Point: 37.4°C
• Appearance: light yellow to light brown/
• Density: 2.1g/cm³
• Vapor Pressure: 0.862mmHg at 25°C
• Refractive Index: 1.848
• Storage Temp.: ?20°C
• Solubility: DMSO: soluble5mg/mL, clear
• CAS DataBase Reference: Galloflavin(CAS DataBase Reference)
• NIST Chemistry Reference: Galloflavin(568-80-9)
• EPA Substance Registry System: Galloflavin(568-80-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 568-80-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 568-80-9 differently. You can refer to the following data:
1. Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent.
2. Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. This compound is suitable for lactate dehydrogenase (LDH) related research.

Biochem/physiol Actions

Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines.

InChI:InChI=1/C12H6O8/c13-4-1-3-7(9(16)8(4)15)10-6(19-11(3)17)2-5(14)12(18)20-10/h1-2,13,15-17H