56805-20-0

Basic information

• Product Name: 5-Isopropyl-2-thioxo-4-imidazolidinone
• Synonyms: 5-Isopropyl-2-thioxo-4-imidazolidinone;5-Isopropyl-2-thioxo-4-imidazolidone
• CAS NO: 56805-20-0
• Molecular Formula: C₆H₁₀N₂OS
• Molecular Weight: 158.22
• Mol File: 56805-20-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.23g/cm³
• Refractive Index: 1.571
• CAS DataBase Reference: 5-Isopropyl-2-thioxo-4-imidazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isopropyl-2-thioxo-4-imidazolidinone(56805-20-0)
• EPA Substance Registry System: 5-Isopropyl-2-thioxo-4-imidazolidinone(56805-20-0)

Safety Data

• Hazardous Substances Data: 56805-20-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H10N2OS/c1-3(2)4-5(9)8-6(10)7-4/h3-4H,1-2H3,(H2,7,8,9,10)

Upstream product

• 1147550-11-5 ammonium thiocyanate 
• 108-24-7 acetic anhydride 
• 516-06-3 D,L-valine 
• 17356-08-0 thiourea 
• 110-89-4 piperidine 
• 503-87-7 2-thiohydantoin 

Relevant articles and documents

Diastereoselective synthesis of pyrrolo[1, 2-c]imidazoles using chiral thiohydantoins, malononitrile, and aldehydes and evaluation of their antioxidant and antibacterial activities

Diastereoselective synthesis of pyrrolo[1,2-c]imidazoles is reported from three-component reaction of chiral thiohydantoins, aldehydes, and malononitrile in the presence of NEt3. The antioxidant properties of the obtained products were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Among the products, compound 4l possessing NH2 and NH groups and bromine atom at 4-position of the aromatic ring displayed the highest antioxidant activity (90%). Also, their antibacterial activities were explored against gram-positive and gram-negative bacteria using disc diffusion method. Among the synthesized compounds, 4a with chlorine atom at para position of the aromatic ring, and methyl group (the smallest alkyl group) at 7-position, displayed the best antibacterial activity against the tested gram-positive bacteria.

Thiazole derivatives

New thiazole derivatives of the general formula I STR1 and their salts with physiologically acceptable acids are described as well as a process for their manufacture. The new compounds exhibit histamine H-2 antagonist activity and may thus be used to inhi