56818-02-1

Basic information

• Product Name: 1,2,3,5-Tetrachloro-4-ethoxybenzene
• Synonyms: 1,2,3,5-Tetrachloro-4-ethoxybenzene;2,4,5,6-Tetrachlorophenylethyl ether
• CAS NO: 56818-02-1
• Molecular Formula: C₈H₆Cl₄O
• Molecular Weight: 259.94
• Mol File: 56818-02-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3,5-Tetrachloro-4-ethoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,5-Tetrachloro-4-ethoxybenzene(56818-02-1)
• EPA Substance Registry System: 1,2,3,5-Tetrachloro-4-ethoxybenzene(56818-02-1)

Safety Data

• Hazardous Substances Data: 56818-02-1(Hazardous Substances Data)

Upstream product

• 704892-43-3 3-ethoxy-2,4,5,6-tetrachloro-benzaldehyde 
• 75-03-6 ethyl iodide 
• 58-90-2 2,3,4,6-tetrachlorophenol 
• 10463-10-2 pentachloro(ethoxy)benzene 
• 704892-44-4 2,3,4,6-tetrachloro-5-hydroxy-benzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 

Relevant articles and documents

Polyhalogenoaromatic Compounds. Part 46. Circumstantial Evidence for the Intermediacy of Radical Anions during the Reaction of Magnesium with ω-Bromoalkoxypolychloro-arenes and -heteroarenes

4-(ω-Bromoalkoxy)tetrachloropyridines, 4-(ω-bromoalkoxy)-3,5-dichloro-2,6-difluoropyridines, and (ω-bromoalkoxy)-pentachlorobenzenes have been prepared by reaction of the appropriate aryl and heteroaryl oxides with 1,ω-dibromoalkanes.The main products from the reactions of the bromoethoxy- or bromopropoxy-tetrachloropyridines with magnesium were the furopyridine (9a) and pyranopyridine (9b), respectively.Elimination of other possible reaction pathways leads to the hypothesis that the cyclisations proceed by electron transfer from magnesium to the tetrachloropyridyl group, followed by nucleophilic displacement of bromide from the side chain.In the absence of a leaving group in the side chain, the radical-anion intermediate leads to a Grignard reagent.