5685-15-4

Basic information

• Product Name: (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID
• Synonyms: (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID
• CAS NO: 5685-15-4
• Molecular Formula: C5H7NO2S2
• Molecular Weight: 177.24
• Mol File: 5685-15-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID(5685-15-4)
• EPA Substance Registry System: (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID(5685-15-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 5685-15-4(Hazardous Substances Data)

Usage

General Description

(4,5-Dihydro-thiazol-2-ylsulfanyl)-acetic acid is a chemical compound that belongs to the class of thiazole derivatives. It is a sulfur-containing organic compound with a thiazole ring and a carboxylic acid group. (4,5-DIHYDRO-THIAZOL-2-YLSULFANYL)-ACETIC ACID has potential pharmacological properties and has been studied for its anti-inflammatory and anti-bacterial activities. It is also used as a building block in the synthesis of various pharmaceutical and agrochemical compounds. The presence of the thiazole ring in its structure makes it an important scaffold for the development of new drugs and bioactive molecules. Overall, (4,5-Dihydro-thiazol-2-ylsulfanyl)-acetic acid is a versatile compound with potential therapeutic and industrial applications.

Upstream product

• 134469-06-0 thiazolidine-2-thione 
• 79-11-8 chloroacetic acid 
• 79-08-3 bromoacetic acid 

Relevant articles and documents

Assessing stereoelectronic effects in dipolar cycloadditions yielding fused thiazolopyridone rings

We report a combined experimental and computational study on the cycloadditions of bicyclic 1,3-thiazolium-4-olates, derived from thiazolidin-2-thiones, with asymmetrically-substituted acetylenes. These results provide further mechanistic insights into the above dipolar cycloadditions and enable an unequivocal characterization by NMR spectroscopy of regiochemical patterns as previous derivatives had substituents at both C-2 (in the dipole) and C-6 (in products). Accordingly, new dihydrothiazolopyrid-2-ones have been obtained from a thioisomünchnone lacking substitution at C-2. With the aim of assessing the steric hindrance as well as the facial stereoselection induced by a bulky group on the Si face (relative to C-7a) of the mesoionic heterocycle, a chiral thioisomünchnone has also been obtained along with the resulting optically active thiazolopyridones. A computational study of these particular cycloadditions, largely based on an NBO analysis, allowed us to evaluate the influence of substituents on intermolecular steric repulsions, charge transfers, as well as solvent effects.