5689-74-7

Basic information

• Product Name: 1,3-diphenylpropylamine
• Synonyms: 1,3-diphenylpropylamine;1,3-Diphenyl-1-propanamine;1,3-Diphenylpropane-1-amine
• CAS NO: 5689-74-7
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.30218
• EINECS: 227-158-5
• Mol File: 5689-74-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 328.3°Cat760mmHg
• Flash Point: 152.8°C
• Appearance: /
• Density: 1.036g/cm³
• Vapor Pressure: 0.000191mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 1,3-diphenylpropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-diphenylpropylamine(5689-74-7)
• EPA Substance Registry System: 1,3-diphenylpropylamine(5689-74-7)

Safety Data

• Hazardous Substances Data: 5689-74-7(Hazardous Substances Data)

Usage

Known for

Antidepressant and anxiolytic (anti-anxiety) properties

Mechanism of action

Increases levels of neurotransmitters in the brain (e.g., serotonin and norepinephrine)

Neurotransmitters involved

Serotonin and norepinephrine

Role in mood regulation

Regulates mood and anxiety

Therapeutic use

Treatment of major depressive disorder and anxiety disorders

Precaution

Misuse or overuse can lead to adverse effects and potential harm

Recommended use

Under the supervision of a qualified healthcare professional

InChI:InChI=1/C15H17N/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10,15H,11-12,16H2

Upstream product

• 1083-30-3 dihydrochalcone 
• 540-69-2 ammonium formate 
• 52939-94-3 (E,E)-1,3-diphenyl-2-propen-1-one oxime 
• 76951-52-5 (1Z,2E)-chalcone oxime 
• 37799-62-5 chalcone phenylhydrazone 
• 64-17-5 ethanol 
• 64-19-7 acetic acid 
• 7664-41-7 ammonia 
• 100-52-7 benzaldehyde 
• 616-75-1 2-benzylmalonic acid 
• 6502-38-1 chalcone oxime 
• 29881-14-9 1,2-diphenyl-cyclopropane 
• 14097-24-6 1,3-diphenylpropan-1-ol 
• 100-42-5 styrene 

Downstream Products

• 108971-44-4 (1,3-diphenyl-propyl)-dimethyl-amine 
• 19141-19-6 N-(1,3-diphenylpropyl)acetamide 
• 38536-49-1 N-(1,3-Diphenyl-prop-1-yl)-harnstoff 
• 19141-19-6 (1R)-(+)-N-[1-phenyl-(3-phenylpropyl)]acetamide 
• 914646-96-1 (E)-tert-butyl 3-(1-oxo-2-(1,3-diphenylpropyl)isoindolin-6-yl)acrylate 
• 1083-30-3 dihydrochalcone 

Relevant articles and documents

Hydroalkylation of Styrenes with Benzylamines by Potassium Hydride

A method for the synthesis of 1,3-diarylpropylamines through hydroalkylation of styrenes with benzylamines by potassium hydride has been developed. The protocol is initiated by solvothermal treatment of benzylamines with KH at 100 °C to generate deprotonated anionic species, which undergo selective C-alkylation with arylalkenes at 0 °C to ambient temperature to afford 1,3-diarylpropylamines as the major product.

Magnetically separable nano Fe3O4 catalyzed direct azidation of allylic and benzylic alcohols followed by copper-catalyzed click reaction

A competent one-pot method comprising magnetically separable nano Fe 3O4 catalyzed direct azidation of allylic and benzylic alcohols followed by the copper-catalyzed click reaction of the corresponding azides with alkynes is reported. This method gave a direct access to several 1,2,3-triazoles starting from various allylic and benzylic alcohols via their respective azides. Georg Thieme Verlag Stuttgart New York.

CATALYST COMPOUNDS

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.