56890-75-6

Basic information

• Product Name: ethyl 2-((5-(2-methoxybenzamido)-1,3,4-thiadiazol-2-yl)thio)acetate
• Synonyms: ethyl 2-((5-(2-methoxybenzamido)-1,3,4-thiadiazol-2-yl)thio)acetate
• CAS NO: 56890-75-6
• Molecular Weight: 353.423
• Mol File: 56890-75-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-((5-(2-methoxybenzamido)-1,3,4-thiadiazol-2-yl)thio)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-((5-(2-methoxybenzamido)-1,3,4-thiadiazol-2-yl)thio)acetate(56890-75-6)
• EPA Substance Registry System: ethyl 2-((5-(2-methoxybenzamido)-1,3,4-thiadiazol-2-yl)thio)acetate(56890-75-6)

Safety Data

• Hazardous Substances Data: 56890-75-6(Hazardous Substances Data)

Upstream product

• 32418-24-9 ethyl 2-[(5-amino-1,3,4-thiadiazol-2-yl)thio]acetate 
• 21615-34-9 2-Methoxybenzoyl chloride 

Relevant articles and documents

Design, synthesis, and biological evaluation of new series of 2-amido-1,3,4-thiadiazole derivatives as cytotoxic agents

A series of novel 1,3,4-thiadiazole derivatives bearing an amide moiety were designed, synthesized, and evaluated for their in vitro antitumor activities against HL-60, SKOV-3 and MOLT-4 human tumor cell lines by MTT assay. Ethyl 2-((5-(4-methoxybenzamido)-1,3,4-thiadiazol- 2-yl)thio)acetate (5f) showed the best inhibitory effect against SKOV-3 cells, with an IC50 value of 19.5 μm. In addition, the acridine orange/ethidium bromide staining assay in SKOV-3 cells suggested that the cytotoxic activity of 5f occurs via apoptosis.