5691-63-4

Basic information

• Product Name: 6α,7β-Dihydroxykaur-16-en-18-oic acid γ-lactone
• Synonyms: Kaur-16-en-18-oic acid, 6,7-dihydroxy-, γ-lactone, (4α,6α,7β)-
• CAS NO: 5691-63-4
• Molecular Formula: C₂₀H₂₈O₃
• Molecular Weight: 316.43
• Mol File: 5691-63-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6α,7β-Dihydroxykaur-16-en-18-oic acid γ-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: 6α,7β-Dihydroxykaur-16-en-18-oic acid γ-lactone(5691-63-4)
• EPA Substance Registry System: 6α,7β-Dihydroxykaur-16-en-18-oic acid γ-lactone(5691-63-4)

Safety Data

• Hazardous Substances Data: 5691-63-4(Hazardous Substances Data)

Upstream product

• 5489-96-3 <2-14C>mevalonic acid 
• 125159-16-2 ent-6β,19-dihydroxykaur-16-ene 
• 82239-37-0 ent-kaur-6,16-diene 
• 77280-78-5 ent-kaura-6,16-dien-19-oic acid 
• 83883-01-6 ent-6α,7α-epoxykaur-16-en-19-oic acid 
• 82239-38-1 ent-18-hydroxykaur-6,16-diene 
• 88125-15-9 ent-18-chlorokaur-6,16-diene 
• 88125-13-7 ent-18-acetoxykaur-6,16-diene 
• 72715-39-0 7β-hydroxykaurenolide mesylate 
• 21435-01-8 7β-hydroxy-(-)-kaur-16-en-19-oic acid 
• 83883-03-8 ent-6β,7β-epoxykaur-16-en-19-oic acid 
• 83883-07-2 methyl ent-6α,7α-epoxykaur-16-en-19-oate 

Downstream Products

• 52475-73-7 7β,11α-dihydroxykaurenolide 
• 19018-46-3 7β,13-dihydroxykaurenolide 
• 90832-21-6 fujenal diacid 
• 83883-02-7 kaurenolide thiobenzoate 
• 85344-33-8 13-hydroxygibberellin A₁₂-7-aldehyde 
• 86948-31-4 7α-(p-bromophenylsulphonyloxy)-13-hydroxykaurenolide 

Relevant articles and documents

THE MICROBIOLOGICAL TRANSFORMATION OF SOME ENT-KAUR-6,16-DIENES BY GIBBERELLA FUJIKUROI

The preparation of ent-kaur-6,16-diene and ent-18-hydroxykaur-6,16-diene from epicandicandiol and of ent-3β,18-dihydroxykaur-6,16-diene from foliol is described.On incubation with Gibberella fujikuroi ent-kaur-6,16-diene gave 7-hydroxykaurenolide and 18-hydroxykaur-6,16-diene afforded 7,18-dihydroxykaurenolide, whilst ent-6α,7α-epoxy-3β,18-dihydroxykaur-16-ene was obtained from ent-3β,18-dihydroxykaur-6,16-diene.The possible biosynthetic significance of the 6,7-epoxidation in kaurenolide is noted. -- Key Word Index - Gibberella fujikuroi; ent-kaur-6,16-dienes; ent-6α,7α-epoxy-3β,18-dihydroxykaur-16-ene; kaurenolide biosynthesis.

THE BIOSYNTHESIS OF KAURENOLIDE DITERPENOIDS BY GIBBERELLA FUJIKUROI

The biosynthesis of 7β-hydroxy- and 7β,18-dihydroxy-kaurenolides from ent-kaur-16-en-19-oic acid has been investigated by incubating unlabelled and labelled putative intermediates with resuspension cultures of Gibberella fujikuroi.The results eliminate pathways which require the loss of oxygen from the 19-oic acid and indicate that the likely pathway is via ent-kaura-6,16-dien-19-oic acid and its ent-6α,7α-epoxide.Key Word Index - Gibberella fujikuroi; resuspension cultures; mutant B1-41a; kaurenoid biosynthesis; 7β-hydroxykaurenolide.