56919-16-5

Basic information

• Product Name: 5-BROMO-2-METHYLBENZENESULFONAMIDE
• Synonyms: 5-BROMO-2-METHYLBENZENESULFONAMIDE
• CAS NO: 56919-16-5
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 250.11
• Mol File: 56919-16-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 390.1°Cat760mmHg
• Flash Point: 189.8°C
• Appearance: /
• Density: 1.658g/cm³
• Vapor Pressure: 2.71E-06mmHg at 25°C
• Refractive Index: 1.599
• CAS DataBase Reference: 5-BROMO-2-METHYLBENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHYLBENZENESULFONAMIDE(56919-16-5)
• EPA Substance Registry System: 5-BROMO-2-METHYLBENZENESULFONAMIDE(56919-16-5)

Safety Data

• Hazardous Substances Data: 56919-16-5(Hazardous Substances Data)

Usage

Description

5-BROMO-2-METHYLBENZENESULFONAMIDE is an organic compound with the molecular formula C7H8BrNO2S. It is a derivative of benzenesulfonamide, featuring a bromine atom at the 5th position and a methyl group at the 2nd position on the benzene ring. 5-BROMO-2-METHYLBENZENESULFONAMIDE is known for its reactivity and utility in the synthesis of various chemical compounds.

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-METHYLBENZENESULFONAMIDE is used as a reagent for the preparation of fluazaindolizine and its analogs, which are important compounds in the development of pharmaceuticals. These compounds have been found to be effective in the control of plant parasitic nematodes, making them valuable for agricultural applications.
Used in Agricultural Industry:
In the agricultural sector, 5-BROMO-2-METHYLBENZENESULFONAMIDE is used as a key intermediate in the synthesis of fluazaindolizine and its analogs. These compounds serve as effective agents for controlling plant parasitic nematodes, which are harmful to crops and can lead to significant yield losses. By incorporating these compounds into pest control strategies, farmers can protect their crops and improve overall agricultural productivity.

InChI:InChI=1/C7H8BrNO2S/c1-5-2-3-6(8)4-7(5)12(9,10)11/h2-4H,1H3,(H2,9,10,11)

Upstream product

• 69321-56-8 5-bromo-2-methyl-benzene-sulfonyl chloride 
• 106-38-7 para-bromotoluene 
• 56919-17-6 4-bromo-toluene-2-sulfonic acid 

Downstream Products

• 62473-92-1 6-bromosaccharin 
• 849067-20-5 N-acetyl-5-bromo-2-methylbenzenesulfonamide 
• 1242134-19-5 4-bromo-2-sulfamoylbenzoic acid 
• 1430628-67-3 2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide 
• 1341040-15-0 6-bromo-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide 
• 1254304-30-7 C₁₆H₁₀BrClF₃N₃O₃S 

Relevant articles and documents

Preparation method and medical application of benzisothiazole and benzothiophene

The invention discloses a preparation method and medical application of benzisothiazole and benzothiophene, and telates to the field of pharmaceutical chemistry. According to the invention, benzisothiazole and benzothiophene are the first type of HIF-2 agonists; compared with a compound M1001 found by the applicant in the earlier stage, the invention has better HIF-2 agonist activity, and has remarkable enhancement activity on expression of mRNA and protein of EPO, VGEF, Glut1, NDRG1 and the like at the downstream of HIF-2, so that the invention can be used for preparing drugs for treating and/or preventing chronic kidney diseases/chronic renal anemia, dyslipidemia and high cholesterol caused by abnormal expression of HIF-2; and the method has a good industrialization prospect.

INHIBITORS OF THE YAP/TAZ-TEAD INTERACTION AND THEIR USE IN THE TREATMENT OF CANCER

The invention relates to compounds of formula (I): wherein R1; R2, R3, R4, R5 and are as defined in the description. The compounds of formula (I) are inhibitors of the YAP/TAZ-TEAD interaction and thu

Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship

In this study, starting from a lead compound discovered by virtual screening, a series of novel heterocyclic substituted benzenesulfonamides were designed and synthesized as new carbonic anhydrase IX (CA IX) inhibitors. Some compounds exhibited potent inh