56929-63-6

Basic information

• Product Name: 8-thia-10,15- diazatetracyclo[7.7.0.02,.011,1]hexadeca- 1(9),2(7),10-trien-16-one
• Synonyms: 8-thia-10,15- diazatetracyclo[7.7.0.02,.011,1]hexadeca- 1(9),2(7),10-trien-16-one
• CAS NO: 56929-63-6
• Molecular Formula: C₁₃H₁₄N₂OS
• Molecular Weight: 246.33
• Mol File: 56929-63-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-thia-10,15- diazatetracyclo[7.7.0.02,.011,1]hexadeca- 1(9),2(7),10-trien-16-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-thia-10,15- diazatetracyclo[7.7.0.02,.011,1]hexadeca- 1(9),2(7),10-trien-16-one(56929-63-6)
• EPA Substance Registry System: 8-thia-10,15- diazatetracyclo[7.7.0.02,.011,1]hexadeca- 1(9),2(7),10-trien-16-one(56929-63-6)

Safety Data

• Hazardous Substances Data: 56929-63-6(Hazardous Substances Data)

Upstream product

• 616-45-5 2-pyrrolidinon 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 5264-35-7 2-methoxy-1-pyrroline 
• 96-48-0 4-butanolide 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 

Downstream Products

• 1296807-48-1 C₂₀H₁₈N₂OS 
• 1296807-49-2 C₂₂H₂₂N₂O₃S 
• 950520-82-8 C₂₂H₂₃N₃OS 

Relevant articles and documents

Thieno[2,3-d]pyrimidin-4-ones 1. condensation of 2,3-dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-7,8-dihydro-pyrrolo[1,2-a]thieno[2, 3-d]pyriminidin-4(6H)-ones with aromatic aldehydes and furfural

2,3-Dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-substituted 8-arylidene-6,7-dihydro-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-4-ones were synthesized by the reaction of 2,3-dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-7,8-dihydropy

Synthesis of isomeric enamine derivatives of fused cycloalkeno thieno[2,3-d]pyrimidin-4(3H)-ones. Stereoelectronic effect on the regioselectivity

A regioselective synthesis of enamine and enaminone derivatives of fused cycloalkeno thieno[2,3-d]pyrimidin-4(3H)-ones is reported. The enamine versus enaminone product in the condensation reaction with N,N-dimethylformamide dimethylacetal (DMFDMA) was shown to depend on the conformation of the cycloalkeno ring fused to the pyrimidinone moiety. The ring conformation and the stereoelectronic effect of the amidine α-protons were studied by X-ray crystallography. In deuterium exchange experiments, the amidine-ketene-N,N- acetal tautomerism was shown to be prohibited with larger (n = 3-4) ring systems consequently yielding the enaminone products. Georg Thieme Verlag Stuttgart.

THIOPHENEPYRIMIDINONES AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS

This invention relates to compounds useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 170β-hydroxyster