5693-27-6

Basic information

• Product Name: 1H-2-Benzopyran-1,4(3H)-dione(9CI)
• Synonyms: 1H-2-Benzopyran-1,4(3H)-dione(9CI);Isochroman-1,4-dione
• CAS NO: 5693-27-6
• Molecular Formula: C₉H₆O₃
• Molecular Weight: 162.14
• Product Categories: PHENYL
• Mol File: 5693-27-6.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1H-2-Benzopyran-1,4(3H)-dione(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-1,4(3H)-dione(9CI)(5693-27-6)
• EPA Substance Registry System: 1H-2-Benzopyran-1,4(3H)-dione(9CI)(5693-27-6)

Safety Data

• Hazardous Substances Data: 5693-27-6(Hazardous Substances Data)

Usage

Natural occurrence

Found in several plants, including tonka beans, sweet clover, and cassia cinnamon

Scent

Sweet, vanilla-like

Uses

Often used in perfumes and fragrances, as well as a flavoring agent in food and beverages (e.g. tobacco and some alcoholic drinks)

Health risks

High levels of consumption associated with liver toxicity and other adverse effects

Regulation

Use as a food additive is regulated in several countries.

Upstream product

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• 208-96-8 acenaphthylene 
• 577-56-0 2-acetyl-benzoic acid 
• 7726-95-6 bromine 
• 4397-55-1 phthalic monoacid monomethyl ester chloride 
• 4376-18-5 Monomethyl phthalate 
• 85-44-9 phthalic anhydride 
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• 420-37-1 trimethoxonium tetrafluoroborate 

Downstream Products

• 98978-88-2 4-(4-hydroxy-1-oxo-1H-isochromen-3-ylmethylene)-2-phenyl-4H-oxazol-5-one 
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• 96276-73-2 3-[2-(3-ethyl-4,5-diphenyl-3H-oxazol-2-ylidene)-ethylidene]-isochroman-1,4-dione 
• 477338-28-6 3-[1-(4,5-Dimethoxy-2-nitro-phenyl)-meth-(Z)-ylidene]-isochroman-1,4-dione 
• 1681-79-4 3-(phenylmethylene)-1H-2-benzopyran-1,4(3H)-dione 
• 19193-15-8 -4-keto-3,4-dihydro-isocumarin 
• 1150-59-0 2-hydroxy-3-phenyl-1,4-naphthoquinone 
• 612-20-4 2-(hydroxymethyl)benzoic acid 
• 1399839-98-5 5H,9H-bis[2]benzopyrano[3,4-e:4′,3′-b]pyridine-5,9-dione 
• 4042-30-2 parvaquone 

Relevant articles and documents

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(3+3)-Annulation of Carbonyl Ylides with Donor–Acceptor Cyclopropanes: Synergistic Dirhodium(II) and Lewis Acid Catalysis

The first (3+3)-annulation process of donor–acceptor cyclopropanes using synergistic catalysis is reported. The Rh2(OAc)4-catalyzed decomposition of diazo carbonyl compounds generated carbonyl ylides in situ. These 1,3-dipoles were c

HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME

Disclosed are chemical entities which are compounds of formula (I); or pharmaceutically acceptable salts thereof; wherein Y, Ra, Ra', Rb, Rc, X1, X2, X3, Rd, Z1, and Z2 have the values described herein and stereochemical configurations depicted at asterisked positions indicate absolute stereochemistry. Chemical entities according to the disclosure can be useful as inhibitors of Sumo Activating Enzyme (SAE). Further provided are pharmaceutical compositions comprising a compound of the disclosure and methods of using the compositions in the treatment of proliferative, inflammatory, cardiovascular, and neurodegenerative diseases or disorders.

NOVEL PROCESS

Disclosed herein is novel process for preparation of atovaquone, which process includes reacting1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.