5696-06-0

Basic information

• Product Name: Methetoin
• Synonyms: Methetoin;Metetoin;5-ethyl-1-methyl-5-phenyl-hydantoin;5-ethyl-1-methyl-5-phenyl-imidazolidine-2,4-dione;5-ethyl-1-methyl-5-phenylimidazolidine-2,4-dione
• CAS NO: 5696-06-0
• Molecular Formula: C₁₂H₁₄N₂O₂
• Molecular Weight: 218.255
• Mol File: 5696-06-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 210°
• Boiling Point: 358.94°C (rough estimate)
• Flash Point: °C
• Appearance: /
• Density: 1.1402 (rough estimate)
• Refractive Index: 1.6660 (estimate)
• PKA: 8.66±0.10(Predicted)
• CAS DataBase Reference: Methetoin(CAS DataBase Reference)
• NIST Chemistry Reference: Methetoin(5696-06-0)
• EPA Substance Registry System: Methetoin(5696-06-0)

Safety Data

• Hazardous Substances Data: 5696-06-0(Hazardous Substances Data)

Usage

Uses

Anticonvulsant.

Brand name

Deltoin (Novartis).

InChI:InChI=1/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)13-11(16)14(12)2/h4-8H,3H2,1-2H3,(H,13,15,16)

Relevant articles and documents

Palladium Catalyzed C-Arylation of Amino Acid Derived Hydantoins

Palladium(II) trifluoroacetate (5 mol %) catalyzes the C-arylation of N,N-disubstituted hydantoins by aryl iodides in good yield. The reaction proceeds through base-promoted enolization of the amino acid derived hydantoins, and the resulting 5,5-disubstituted hydantoins may be deprotected at one or both N atoms to yield biologically active structures or alternatively hydrolyzed to the parent α-aryl α-amino acids. The reaction is successful with a variety of parent amino acids and a range of electron-rich and electron-poor aryl iodides.