56972-68-0

Basic information

• Product Name: Propanoyl chloride, 2-(phenylmethoxy)-
• Synonyms: 2-benzyloxy-propionyl chloride;2-Benzyloxy-propionylchlorid;O-benzyllactoyl chloride
• CAS NO: 56972-68-0
• Molecular Formula: C10H11ClO2
• Molecular Weight: 198.649
• Mol File: 56972-68-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 79-81 °C(Press: 0.5 Torr)
• Density: 1.165±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Propanoyl chloride, 2-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoyl chloride, 2-(phenylmethoxy)-(56972-68-0)
• EPA Substance Registry System: Propanoyl chloride, 2-(phenylmethoxy)-(56972-68-0)

Safety Data

• Hazardous Substances Data: 56972-68-0(Hazardous Substances Data)

Upstream product

• 20194-18-7 sodium phenyl-methanolate 
• 100-39-0 benzyl bromide 
• 33106-32-0 2-(benzyloxy)propanoic acid 

Downstream Products

• 100060-27-3 3-benzyloxy-1-diazo-butan-2-one 
• 78957-59-2 2',6'-di-tert-butyl-4'-methylphenyl (RS)-2-(benzyloxy)propanoate 
• 116505-10-3 (5S,6S)-6-((S)-1-Benzyloxy-ethyl)-5-methyl-4-pyrrolidin-1-yl-5,6-dihydro-pyran-2-one 
• 116505-10-3 (5S,6S)-6-((R)-1-Benzyloxy-ethyl)-5-methyl-4-pyrrolidin-1-yl-5,6-dihydro-pyran-2-one 
• 53346-05-7 2-(benzyloxy)propanal 
• 61183-18-4 N-(α-Benzyloxypropionyl)-DL-threonin-methylester 
• 61183-19-5 2-(2-benzyloxy-propionylamino)-3-oxo-butyric acid methyl ester 
• 61183-20-8 2-(1-benzyloxy-ethyl)-5-methyl-oxazole-4-carboxylic acid methyl ester 
• 95481-44-0 (2R,5S)-2-Methyl-5-phenyl-dihydro-furan-3-one 
• 95481-44-0 (2S,5S)-2-Methyl-5-phenyl-dihydro-furan-3-one 
• 78957-76-3 (2R,3R)-2-Benzyloxy-3-hydroxy-2-methyl-4-phenyl-pentanoic acid 2,6-di-tert-butyl-4-methyl-phenyl ester 

Relevant articles and documents

Mutual kinetic resolution of 3-methyl-3,4-dihydro-2H-1,4-benzoxazines and 2-alkoxyacyl chlorides

[Figure not available: see fulltext.] Stereoselective acylation of racemic 3-methyl-3,4-dihydro-2Н-1,4-benzoxazine and its 7,8-difluoro-substituted analog with racemic 2-alkoxyacyl chlorides was stidied. The reactions of 3-methyl-3,4-dihydro-2H-1,4-benzoxazines with 2-methoxyisopentanoyl chloride were found to be more selective (selectivity factor s 31–32) compared to the acylation with other studied propanoyl chlorides (s 18–21). This fact was probably caused by the significant steric hindrance due to the isopropyl substituent in acyl chloride compared to the methyl group in reagents derived from propanoic acid.

AZACYCLIC COMPOUNDS AS INHIBITORS OF SENSORY NEURONE SPECIFIC CHANNELS

Compounds of the formula (I), and pharmaceutically acceptable salts thereof, are found to be antagonists of SNS sodium channels. They are therefore useful as analgesic and neuroprotective agents wherein: X is -N- or -CH-; n is from 0 to 3.

THE STUDIES OF METAL ION CATALYZED CARBON-HYDROGEN INSERTION OF α-ALKOXY-α'-DIAZOKETONES DERIVED FROM MANDELIC AND LACTIC ACIDS

The cupric acetylacetonate is the best catalyst to induce the carbon-hydrogen inserted reaction for the α-alkoxy-α'-diazoketones derivatives (5 and 6).The side reactions such as aromatic carbon-hydrogen insertion and rearrangement could be prevented.