56979-57-8Relevant articles and documents
Chromen-based TNF-α converting enzyme (TACE) inhibitors: Design, synthesis, and biological evaluation
Chun, Kwangwoo,Park, Song-Kyu,Kim, Hwan Mook,Choi, Yongseok,Kim, Myung-Hwa,Park, Chun-Ho,Joe, Bo-Young,Chun, Tae Gyu,Choi, Hyun-Moo,Lee, Hee-Yoon,Hong, Sung Hee,Kim, Myung Sook,Nam, Ky-Youb,Han, Gyoonhee
, p. 530 - 535 (2008)
A series of coumarin types MMP inhibitors were designed based on gelastatin hydroxamates (1) and evaluated for TACE, cellular TNF-α, and NO inhibitory activities. Among them, compounds 9b had potent inhibitory activities in enzymatic and cellular assays a
4-(2,4-BIS(2-HYDROXYPHENYL)-1H-IMIDAZOL-1-YL)BENZOIC ACID DERIVATIVES AS NOVEL IRON CHELATORS
-
Page/Page column 57; 58, (2020/10/20)
The invention relates to novel compounds of the general formula (I) pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as iron chelators, more particularly for the use in the prophylaxis and/or treatm
Syntheses and anti-inflammatory activity of natural 1,3-diarylpropenes
Jung, Jong-Woon,Kim, Jin-Kyung,Jun, Jong-Gab
, p. 632 - 637 (2016/06/09)
First syntheses of five natural 1,3-diarylpropenes (cinnamylphenols) 2-4, 7, and 8 along with synthesis of two other natural 1,3-diarylpropenes 1 and 5 and E-isomer of mucronulastyrene (6) were achieved by Friedel- Crafts alkylation as a key step. Subsequ