57015-17-5Relevant articles and documents
Regioselective Synthesis of α-Functional Stilbenes via Precise Control of Rapid cis- trans Isomerization in Flow
Lee, Hyune-Jea,Yonekura, Yuya,Kim, Nayoung,Yoshida, Jun-Ichi,Kim, Heejin
, p. 2904 - 2910 (2021/05/05)
The rapid cis-trans isomerization of α-anionic stilbene was regioselectively controlled by using flow microreactors, and its reaction with various electrophiles was conducted. The reaction time was precisely controlled within milliseconds to seconds at -50 °C to selectively give the cis- or trans-isomer in high yields. This synthetic method in flow was well-applied to synthesize precursors of commercial drug compound, (E)- and (Z)-tamoxifen with high regioselectivity and productivity.
THE PALLADIUM-CATALYZED REDUCTIVE ADDITION OF ARYL IODIDES TO CARBON-CARBON TRIPLE BONDS: A STRUCTURAL STUDY ON 1,2,3-TRIPHENYL-2-PROPEN-1-OL, THE PRODUCT OF syn-ADDITION
Arcadi, Antonio,Cacchi, Sandro,Ianelli, Sandra,Marinelli, Fabio,Nardelli, Mario
, p. 725 - 730 (2007/10/02)
The crystal structure of 1,2,3-triphenyl-2-propen-1-ol, derived from the palladium-catalyzed reductive addition of phenyl iodide to 1,3-diphenyl-2-propyn-1-ol, has been determined using single-crystal X-ray diffractometric data (Cu-Kα): M = 286