57018-82-3

Basic information

• Product Name: 1-(6-amino-purin-9-yl)-O⁵-(4,4'-dimethoxy-trityl)-β-D-1-deoxy-arabinofuranose
• Synonyms: 1-(6-amino-purin-9-yl)-O⁵-(4,4'-dimethoxy-trityl)-β-D-1-deoxy-arabinofuranose
• CAS NO: 57018-82-3
• Molecular Weight: 569.617
• Mol File: 57018-82-3.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 1-(6-amino-purin-9-yl)-O⁵-(4,4'-dimethoxy-trityl)-β-D-1-deoxy-arabinofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-amino-purin-9-yl)-O⁵-(4,4'-dimethoxy-trityl)-β-D-1-deoxy-arabinofuranose(57018-82-3)
• EPA Substance Registry System: 1-(6-amino-purin-9-yl)-O⁵-(4,4'-dimethoxy-trityl)-β-D-1-deoxy-arabinofuranose(57018-82-3)

Safety Data

• Hazardous Substances Data: 57018-82-3(Hazardous Substances Data)

Upstream product

• 58-61-7 adenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 5536-17-4 arabinosyl adenine 
• 17331-18-9 N'-[9-((3aR,4R,6R,6aR)-2-Dimethylamino-6-hydroxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-yl]-N,N-dimethyl-formamidine 

Downstream Products

• 219677-67-5 5'-O-dimethoxytrityl-2'-O,3'-O,6-N-triphenoxyacetyladenosine 
• 6216-67-7 Adenosin-5'-phosphorsaeure-(N-benzyloxycarbonyl-L-leucinolat) 
• 1054645-97-4 Phenoxy-acetic acid (2R,3R,4R,5R)-5-[((S)-2-benzyloxycarbonylamino-4-methyl-pentyloxy)-hydroxy-phosphoryloxymethyl]-4-(2-phenoxy-acetoxy)-2-[6-(2-phenoxy-acetylamino)-purin-9-yl]-tetrahydro-furan-3-yl ester 
• 1446484-46-3 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-4-(phenyldisulfanyl)butanoate 
• 1446484-45-2 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-4-(tert-butyldisulfanyl)butanoate 
• 1446484-44-1 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-4-(isopropyldisulfanyl)butanoate 
• 1446484-43-0 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-4-(methyldisulfanyl)butanoate 
• 1333389-11-9 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate 
• 1333389-19-7 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 3-(4-benzoylphenyl)-2-((tert-butoxycarbonyl)amino)propanoate 
• 1333389-17-5 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-azido-3-phenylpropanoate 
• 1333389-15-3 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)(methyl)amino)-3-phenylpropanoate 
• 1333389-13-1 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 3-(4-azidophenyl)-2-((tert-butoxycarbonyl)amino)propanoate 
• 1333389-12-0 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-3-yl 2-((tert-butoxycarbonyl)amino)-4-methylpentanoate 
• 1333389-20-0 (S)-(2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl 2-amino-3-(4-azidophenyl)propanoate 

Relevant articles and documents

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A solvent free and selective method for preparation of triphenylmethyl ethers of alcohols and nucleosides

A very simple and efficient method is described for protection of alcohols and nucleosides with trityl(triphenylmethyl), mono and dimethoxytrityl chlorides in the presence of triethylamine under microwave irradiation. High selectivity was observed for tritylation of 5'-OH function of nucleosides.

Synthesis of modified nucleosides for incorporation of formyletheno and carboxyetheno adducts of adenine nucleosides into oligonucleotides

Three protected derivatives of 1,N6-ethenoadenine nucleosides, viz. 3-[5-O-(4,4′-dimethoxytrityl) of 7-formyl-(1) and 7-(1,2- diacetyloxypropyl)-2′-deoxyadenosine (2), and 3-[5-O-(4,4′- dimethoxytrityl)-2-O-(tert-butyldimethylsilyl)-7-(ethoxycarbonyl)adenosine (3), expected to allow introduction of formyletheno and carboxyethenoadenine adducts into oligonucleotides by the conventional phosphoramidite chemistry, have been synthesized. Copyright Taylor & Francis Group, LLC.