570390-94-2

Basic information

• Product Name: Carbamic acid, (3-chloro-2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, (3-chloro-2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI);tert-butyl 3-chloro-2-hydroxypropylcarbaMate;2-Methyl-2-propanyl (3-chloro-2-hydroxypropyl)carbamate
• CAS NO: 570390-94-2
• Molecular Formula: C₈H₁₆ClNO₃
• Molecular Weight: 209.67054
• Product Categories: N-BOC
• Mol File: 570390-94-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Carbamic acid, (3-chloro-2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (3-chloro-2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI)(570390-94-2)
• EPA Substance Registry System: Carbamic acid, (3-chloro-2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI)(570390-94-2)

Safety Data

• Hazardous Substances Data: 570390-94-2(Hazardous Substances Data)

Upstream product

• 1125824-66-9 C₁₅H₂₀ClNO₃ 
• 34619-03-9 tert-butyldicarbonate 
• 62037-46-1 rac-1-amino-3-chloro-2-propanol hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 570391-01-4 (S)-[[3-[4-(2,3-dihydro-1,1-dioxido-4H-1,4-thiazin-4-yl)-3,5-difluorophenyl]-2-oxo-5-oxazolidinyl]methyl]carbamic acid, 1,1-dimethylethyl ester 
• 148982-76-7 tert-butyl N-(2-oxiranylmethyl)carbamate 

Relevant articles and documents

A more than the penem matching bends down the ester side chain new synthetic method

The invention discloses a novel synthetic method of a tebipenem pivoxil side chain. The method employs cheap and easily available raw material, has simple experimental operations, high overall yield and is applicable to industrialized production.

Truly catalytic and chemoselective cleavage of benzylidene acetal with phosphomolybdic acid supported on silica gel

Phosphomolybdic acid supported on silica gel provides a truly catalytic method for the chemoselective cleavage of benzylidene acetals having sensitive functional groups under mild conditions. It is easy to perform on large scale owing to minimal catalyst loading (0.5 mol-%). Several sensitive functional groups such as TBDPS ether, -OMs, -OAc, allyl ether, N-Boc, N-Fmoc and N-Cbz are stable under the reaction conditions. In addition, benzylidene acetal is selectively cleaved in the presence of isopropylidene ketal. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.