57102-98-4Relevant articles and documents
Tert -Butylhydroperoxide-Mediated Oxidation of Carbazole-3-carboxyaldehydes
Meesala, Ramu,Arshad, Ahmad Saifuddin Mohamad,Pichika, Mallikarjuna Rao,Mordi, Mohd Nizam,Mansor, Sharif Mahsufi
, p. 1084 - 1086 (2018)
Oxidation of carbazole-3-carboxyaldehydes promoted by a 70% aqueous solution of tert -butylhydroperoxide leads to the corresponding carbazole-3-carboxylic acids in good yields. This transition-metal-free oxidation protocol is attractive for the synthesis of pharmaceutically important carbazole analogues.
MODIFIED CARBAZOLES AS THERAPEUTIC AGENTS
-
Paragraph 0177, (2020/01/08)
This disclosure relates to compounds that target microtubules, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases. More particularly, this disclosure relates to modified carbazole compounds and pharmaceutical compositions thereof, methods of targeting microtubules with these compounds, and methods of treating diseases affected by microtubule disruption.
Copper(II)-Catalyzed Iodinations of Carbazoles: Access to Functionalized Carbazoles
Przypis, Lukasz,Walczak, Krzysztof Zdzislaw
, (2019/02/14)
A copper-catalyzed iodination of carbazoles has been developed. Barluenga's reagent IPy2BF4 is used to generate a soft electrophilic halonium species for the iodination of the carbazoles. This report represents the first concept of copper-catalyst-promoted electrophilic halogenation of carbazoles. We demonstrated numerous applications of this methodology synthesizing diverse carbazole derivatives, i.e., both electron-rich and electron-deficient systems.