5716-14-3Relevant articles and documents
The Escherichia coli glucuronylsynthase promoted synthesis of steroid glucuronides: Improved practicality and broader scope
Ma, Paul,Kanizaj, Nicholas,Chan, Shu-Ann,Ollis, David L.,McLeod, Malcolm D.
supporting information, p. 6208 - 6214 (2014/08/05)
A library of steroid glucuronides was prepared using the glucuronylsynthase derived from Escherichia coli β-glucuronidase, followed by purification using solid-phase extraction. A representative range of steroid substrates were screened for synthesis on t
Escherichia coli glucuronylsynthase: An engineered enzyme for the synthesis of β-glucuronides
Wilkinson, Shane M.,Liew, Chu W.,Mackay, Joel P.,Salleh, Hamzah M.,Withers, Stephen G.,McLeod, Malcolm D.
supporting information; experimental part, p. 1585 - 1588 (2009/04/10)
The glycosynthase derived from E. coli β-glucuronidase catalyzes the glucuronylation of a range of primary, secondary, and aryl alcohols with moderate to excellent yields. The procedure provides an efficient, stereoselective, and scalable single-step synthesis of β-glucuronides under mild conditions.
