57177-79-4

Basic information

• Product Name: Boc-Pro-D-Phe-OMe
• Synonyms: Boc-Pro-D-Phe-OMe
• CAS NO: 57177-79-4
• Molecular Weight: 376.453
• Mol File: 57177-79-4.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: Boc-Pro-D-Phe-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-Pro-D-Phe-OMe(57177-79-4)
• EPA Substance Registry System: Boc-Pro-D-Phe-OMe(57177-79-4)

Safety Data

• Hazardous Substances Data: 57177-79-4(Hazardous Substances Data)

Upstream product

• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 3392-10-7 tert-butoxycarbonyl-L-proline N-hydroxysuccinimide ester 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 13033-84-6 D-phenylalanine methyl ester hydrochloride 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 96792-04-0 (-)-(S)-tert-butyl-2-<(hydroxyamino)carbonyl>pyrrolidine-1-carboxylate 
• 133010-05-6 tert-butyl 2-(fluorocarbonyl)pyrrolidine-1-carboxylate 

Downstream Products

• 564489-29-8 (S)-tert-butyl 2-(((S)-1-((S)-3-hydroxy-1-methoxy-1-oxopropane-2-yl-amino)-1-oxo-3-phenylpropane-2-yl)carbamoyl)pyrrolidine-1-carboxylate 

Relevant articles and documents

Pro-phe derivatives as organocatalysts in asymmetric aldol reaction

The aldol reaction which is the most important one among the C-C bond forming reactions, is widely used by synthetic organic chemists to obtain β-hydroxycarbonyl compounds which are important starting components for biologically active compounds in optica

Synthesis of new di- And triamides as potential organocatalysts for asymmetric aldol reaction in water

New di- or triamide organocatalysts derived from (L)-proline were synthesized and successfully used in the direct asymmetric aldol reaction of aliphatic ketones and aromatic aldehydes in water at 0 °C in the presence of benzoic acid as co-catalyst. (S)-me

Phenysilane and Silicon Tetraacetate: Versatile Promotors for Amide Synthesis

Phenylsilane was reevaluated as a useful coupling reagent for amide synthesis. At room temperature, a wide range of amides and peptides were obtained in good to excellent yields (up to 99 %). For the first time, Weinreb amides synthesis mediated by a hydrosilane were also documented. Comparative experiments with various acetoxysilanes suggested the involvement of a phenyl-triacyloxysilane. From this mechanistic study, silicon tetraacetate was shown as an efficient amine acylating agent.