57198-98-8

Basic information

• Product Name: Benzoic acid, 2,4,6-tris(1-methylethyl)-, methyl ester
• Synonyms: methyl 2,4,6-triisopropylbenzoate;2,4,6-triisopropyl-benzoic acid methyl ester;2,4,6-Triisopropyl-benzoesaeure-methylester;Methyl-2,4,6-triisopropylbenzoat
• CAS NO: 57198-98-8
• Molecular Formula: C17H26O2
• Molecular Weight: 262.392
• Mol File: 57198-98-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,4,6-tris(1-methylethyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,4,6-tris(1-methylethyl)-, methyl ester(57198-98-8)
• EPA Substance Registry System: Benzoic acid, 2,4,6-tris(1-methylethyl)-, methyl ester(57198-98-8)

Safety Data

• Hazardous Substances Data: 57198-98-8(Hazardous Substances Data)

Upstream product

• 49623-71-4 2,4,6-triisopropylbenzoic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 74-88-4 methyl iodide 
• 165904-22-3 4,4,5,5-tetramethyl-2-phenethyl-1,3,2-dioxaborolane 
• 74-89-5 methylamine 
• 87100-15-0 cyclohexylboronic acid pinacol ester 
• 63846-79-7 (tributylstannyl)methyl 2,4,6-triisopropylbenzoate 
• 100-39-0 benzyl bromide 
• 75-15-0 carbon disulfide 
• 111-71-7 heptanal 
• 1133931-84-6 C₂₉H₅₁⁽²⁾HO₂Sn 

Downstream Products

• 63846-75-3 C₁₇H₂₅⁽²⁾HO₂ 

Relevant articles and documents

Mild Esterification of Carboxylic Acids via Continuous Flow Diazotization of Amines

A new continuous flow protocol for the diazotization of methylamine with 1,3-propanedinitrite in THF is reported. The synthesis of methyl esters was achieved in high yields from a variety of carboxylic acids in 20 min at 90 °C. Additionally, this protocol was extended to other aryl and alkyl amines, namely secondary amines, to produce various substituted esters in high yield using 2-MeTHF as a solvent. The reaction conditions were compatible with many functional groups, namely nitrogen-containing heterocycles, alkynes, alkenes, alcohols, and phenols. Mechanistic investigations reveal that the reaction appears to proceed through a transient diazonium species rather than a diazo intermediate.

Visible-Light-Driven Carboxylation of Aryl Halides by the Combined Use of Palladium and Photoredox Catalysts

A highly useful, visible-light-driven carboxylation of aryl bromides and chlorides with CO2 was realized using a combination of Pd(OAc)2 as a carboxylation catalyst and Ir(ppy)2(dtbpy)(PF6) as a photoredox catalyst. This carboxylation reaction proceeded in high yields under 1 atm of CO2 with a variety of functionalized aryl bromides and chlorides without the necessity of using stoichiometric metallic reductants.

Enantiopure chiral (2,4,6-triisopropylbenzoyl)oxy-[D1] methyllithium: Configurational stability, reactions, and mechanistic studies

The configurational stability of enantiopure chiral (2,4,6- triisopropylbenzoyl)oxy-[D1]methyllithium generated by a tin-lithium exchange was tested on the macroscopic time scale, employing trapping experiments with benzaldehyde. It was found t