573-43-3

Basic information

• Product Name: Ethanedione, bis(2-fluorophenyl)-
• CAS NO: 573-43-3
• Molecular Formula: C14H8F2O2
• Molecular Weight: 246.213
• Mol File: 573-43-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Ethanedione, bis(2-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanedione, bis(2-fluorophenyl)-(573-43-3)
• EPA Substance Registry System: Ethanedione, bis(2-fluorophenyl)-(573-43-3)

Safety Data

• Hazardous Substances Data: 573-43-3(Hazardous Substances Data)

Upstream product

• 24133-56-0 1,2-bis(2-fluorophenyl)-1,2-ethanediol 
• 445-27-2 2'-Fluoroacetophenone 
• 1072-85-1 o-fluorobromobenzene 
• 161864-41-1 1,2-bis(2-fluorophenyl)ethanone 
• 138036-92-7 2-(2-fluorophenyl)-1,3-dithiane 
• 125652-30-4 1,2-bis(2-fluorophenyl)-2-hydroxyethan-1-one 
• 144461-84-7 2-(2-fluorophenyl)-2-(α-hydroxy-2-fluorobenzyl)-1,3-dithiane 
• 394-35-4 methyl 2-fluorobenzoate 
• 446-52-6 2-Fluorobenzaldehyde 

Downstream Products

• 125652-30-4 1,2-bis(2-fluorophenyl)-2-hydroxyethan-1-one 
• 668991-38-6 (S)-1,2-bis(2-fluorophenyl)-2-hydroxyethan-1-one 
• 1603-61-8 (2-cyclohexyl-ethyl)-benzene 
• 3321-50-4 1,2-dicyclohexylethane 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 144461-88-1 5,5-bis-(2-fluorophenyl)-hydantoin 

Relevant articles and documents

Ring Closing Metathesis Approach for the Synthesis of o-Terphenyl Derivatives

A linear synthesis of o-terphenyl derivatives has been delineated using ring closing metathesis (RCM) as the key step. In this approach, benzil derivatives upon allyl Grignard addition provides diphenyl-1,2-diallyl dihydroxy derivatives which undergo ring closing metathesis to afford tetrahydro terphenyl derivatives. Aromatization-driven dehydration then leads to a diverse set of electron rich and electron deficient o-terphenyls. Furthermore, oxidative coupling of electron rich o-terphenyls provides the corresponding triphenylene derivatives.

Base-Free Asymmetric Transfer Hydrogenation of 1,2-Di- and Monoketones Catalyzed by a (NH)2P2-Macrocyclic Iron(II) Hydride

The hydride isonitrile complex [FeH(CNCEt3)(1 a)]BF4 (2) containing a chiral P2(NH)2 macrocycle (1 a), in the presence of 2-propanol as hydrogen donor, catalyzes the base-free asymmetric transfer hydrogenation (ATH) of prostereogenic ketones to alcohols and the hemihydrogenation of benzils to benzoins, which contain a base-labile stereocenter. Benzoins are formed in up to 83 % isolated yield with enantioselectivity reaching 95 % ee. Ketones give the same enantioselectivity observed with the parent catalytic system [Fe(CNCEt3)2(1 a)] (3 a) that operates with added NaOtBu.

Chiral Frustrated Lewis Pairs Catalyzed Highly Enantioselective Hydrosilylations of 1,2-Dicarbonyl Compounds

A highly enantioselective hydrosilylation of 1,2-dicarbonyl compounds was successfully realized for the first time utilizing the combination of tricyclohexylphosphine and chiral alkenylborane derived in situ from diyne as a frustrated Lewis pair catalyst. A variety of optically active α-hydroxy ketones and esters were obtained in 52-98% yields with 86-99% ee's.