5730-75-6

Basic information

• Product Name: METHYL 4'-NITRO[1,1'-BIPHENYL]-4-CARBOXYLATE
• Synonyms: IFLAB-BB F2108-0025;METHYL 4'-NITRO[1,1'-BIPHENYL]-4-CARBOXYLATE;Methyl 4-(4-nitrophenyl)benzoate
• CAS NO: 5730-75-6
• Molecular Formula: C₁₄H₁₁NO₄
• Molecular Weight: 257.24
• Mol File: 5730-75-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 188-190°C
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 4'-NITRO[1,1'-BIPHENYL]-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4'-NITRO[1,1'-BIPHENYL]-4-CARBOXYLATE(5730-75-6)
• EPA Substance Registry System: METHYL 4'-NITRO[1,1'-BIPHENYL]-4-CARBOXYLATE(5730-75-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5730-75-6(Hazardous Substances Data)

Usage

General Description

Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is a chemical compound with the molecular formula C15H11NO4. It is a nitro-substituted aromatic ester with a biphenyl structure. Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate is commonly used in organic synthesis and pharmaceutical research as a precursor for various reactions. It is also used in the production of pharmaceuticals and agrochemicals. Methyl 4'-nitro[1,1'-biphenyl]-4-carboxylate has potential applications in the development of novel materials and drugs due to its unique structural features and reactivity. Additionally, it may be used as a reference standard in analytical chemistry and quality control processes.

Upstream product

• 586-78-7 para-nitrophenyl bromide 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 67-56-1 methanol 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 92-89-7 4'-nitro-biphenyl-4-carboxylic acid 
• 5730-76-7 methyl 4’-amino-[1,1’-biphenyl]-4-carboxylate 
• 5730-78-9 4-(4-aminophenyl)benzoic acid 
• 1332882-94-6 4'-({(R)-2,3-bis[di(tert-butoxycarbonylmethyl)amino]propionyl}amino)-1,1'-biphenyl-4-carboxylic acid benzyl ester 
• 137058-70-9 4'-amino-1,1'-biphenyl-4-carboxylic acid benzyl ester 
• 1204-78-0 4-(4-methylphenyl)aniline 
• 2143-88-6 4-nitro-4'-methyl-1,1'-biphenyl 

Relevant articles and documents

The suzuki-miyaura reaction performed using a palladium-n-heterocyclic carbene catalyst and a weak inorganic base

N-Heterocyclic carbenes (NHCs) have been shown to be useful ligands for the Suzuki-Miyaura cross-coupling at low catalyst loadings. We now report that the commercially available and air-stable [Pd(IPr)(cin)Cl] pre-catalyst permits the formation of various functionalized biaryls from aryl chlorides and boronic acids (37 examples) under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base. [Pd(IPr)(cin)Cl] permits an operationally simple Suzuki-Miyaura reaction under very mild conditions using a mixture of ethanol/water as solvent and an inorganic base.

Dynamics of the glycosidic bond: Conformational space of lactose

The dynamics of the glycosidic bond of lactose was studied by a paramagnetic tagging-based NMR technique, which allowed the collection of an unusually large series of NMR data for a single compound. By the use of distance- and orientation-dependent residual dipolar couplings and pseudocontact shifts, the simultaneous fitting of the probabilities of computed conformations and the orientation of the magnetic susceptibility tensor of a series of lanthanide complexes of lactose show that its glycosidic bond samples syn/syn, anti/syn and syn/anti φ/I regions of the conformational space in water. The analysis indicates a higher reliability of pseudocontact shift data as compared to residual dipolar couplings with the presently available weakly orienting paramagnetic tagging technique. The method presented herein allows for an improved understanding of the dynamic behaviour of oligosaccharides. Copyright

Use of functionalized onium salts as a soluble support for organic synthesis

The invention relates to the use of a onium salt functionalized by at least one organic function, as a soluble support, in the presence of at least one organic solvent, for organic synthesis of a molecule, in a homogenous phase, by at least one transformation of said organic function. The onium salt enables the synthesized molecule to be released. The onium salt is present in liquid or solid form at room temperature and corresponds to formula A1+, X1?, wherein A1+ represents a cation and X1? represents an anion.