57319-72-9

Basic information

• Product Name: (2E)-2-(1H-benzimidazol-2-yl)-3-furan-2-ylprop-2-enenitrile
• Synonyms: (2E)-2-(1H-Benzimidazol-2-yl)-3-(2-furyl)acrylonitrile; 1H-Benzimidazole-2-acetonitrile, alpha-(2-furanylmethylene)-, (alphaE)-
• CAS NO: 57319-72-9
• Molecular Formula: C₁₄H₉N₃O
• Molecular Weight: 235.2408
• Mol File: 57319-72-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 456.8°C at 760 mmHg
• Flash Point: 230°C
• Density: 1.349g/cm³
• Vapor Pressure: 1.58E-08mmHg at 25°C
• Refractive Index: 1.728
• CAS DataBase Reference: (2E)-2-(1H-benzimidazol-2-yl)-3-furan-2-ylprop-2-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-(1H-benzimidazol-2-yl)-3-furan-2-ylprop-2-enenitrile(57319-72-9)
• EPA Substance Registry System: (2E)-2-(1H-benzimidazol-2-yl)-3-furan-2-ylprop-2-enenitrile(57319-72-9)

Safety Data

• Hazardous Substances Data: 57319-72-9(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 4414-88-4 1H-benzimidazol-2-acetonitrile 
• 104030-32-2 C₁₄H₉N₃O 
• 95-54-5 1,2-diamino-benzene 

Relevant articles and documents

Design and structure-activity relationships anticandidosic of diazaheteroaryl functionalized by Micha?l acceptors

Benzimidazole and imidazopyridine heterocycles associated with Micha?l acceptors have shown strong anticandidosic potential in our previous work. After a decade of research, we have designed, synthesized and evaluated the anticandidosic activities of seve

Anhydrous zinc chloride catalysis in carbonyl-methylene condensations: Synthesis of arylidene acetonitriles and arylidene heterocycles

Anhydrous zinc chloride has been found to be an efficient catalyst in carbonyl-methylene condensation reactions.The synthesis of arylidene acetonitriles (6a-g, 7a-g) and arylidene heterocycles (8a-e, 9a-e) have been accomplished in high yields and good purity.

Reactions of cyanomethylbenzimidazoles. Part II. Reaction of cyanomethylbenzimidazoles with aldehydes methylketones and nitroso compounds.

Position of CH2CN group in the benzimidazole system determines the activity of hydrogen atoms of CH2 group in condensation reactions. Some of the obtained compounds show high tuberculostatic activity.