57325-22-1

Basic information

• Product Name: sec-Pentylbromomagnesium
• Synonyms: (1-Methylbutyl)magnesium bromide;sec-Pentylbromomagnesium
• CAS NO: 57325-22-1
• Molecular Formula: C₅H₁₁BrMg
• Molecular Weight: 0
• Mol File: 57325-22-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: sec-Pentylbromomagnesium(CAS DataBase Reference)
• NIST Chemistry Reference: sec-Pentylbromomagnesium(57325-22-1)
• EPA Substance Registry System: sec-Pentylbromomagnesium(57325-22-1)

Safety Data

• Hazardous Substances Data: 57325-22-1(Hazardous Substances Data)

Usage

Description

sec-Pentylbromomagnesium, also known as 2-Pentylmagnesium Bromide, is an organomagnesium compound that serves as a crucial intermediate in the synthesis of various organic compounds, particularly those with pharmaceutical and chemical applications. It is characterized by its reactivity and ability to form Grignard reagents, which are widely used in organic synthesis.

Uses

Used in Pharmaceutical Industry:
sec-Pentylbromomagnesium is used as an intermediate for the synthesis of 3-Methyl-2-hexanamine (M263665), which is an essential component in the production of Plumbagin-d3 (P627002). Plumbagin-d3 is a labeled version of Plumbagin (P627000), a compound known for its ability to induce apoptosis in cancer cells and inhibit NADPH oxidase 4 in a timeand dose-dependent manner. This makes sec-Pentylbromomagnesium a valuable compound in the development of anticancer drugs and therapies.
Used in Chemical Synthesis:
In the field of chemical synthesis, sec-Pentylbromomagnesium is utilized as a versatile reagent for the preparation of various organic compounds. Its ability to form Grignard reagents allows for the efficient synthesis of a wide range of molecules, making it an indispensable tool in the chemical industry.

Upstream product

• 107-81-3 2-bromopentane 
• 7439-95-4 magnesium 

Downstream Products

• 3302-03-2 4-Methyl-heptansaeure 
• 817-91-4 4-methyl-1-heptanol 
• 15869-96-2 5,5-dimethyloctane 
• 1338362-98-3 2-(N,N-difluoroamino)pentane 
• 6175-51-5 5-methyl-4-octanone 
• 137018-79-2 4'-Octyloxy-biphenyl-4-carboxylic acid 4-((R)-(S)-pentane-2-sulfinyl)-phenyl ester 
• 137018-79-2 4'-Octyloxy-biphenyl-4-carboxylic acid 4-((R)-(R)-pentane-2-sulfinyl)-phenyl ester 
• 129470-37-7 4-Octyloxy-benzoic acid 4-((R)-(S)-pentane-2-sulfinyl)-phenyl ester 
• 129470-36-6 4-Octyloxy-benzoic acid 4-((R)-(R)-pentane-2-sulfinyl)-phenyl ester 
• 129470-32-2 4-((S)-Pentane-2-sulfinyl)-phenol 
• 129470-32-2 4-((R)-Pentane-2-sulfinyl)-phenol 
• 29182-84-1 1-Methoxy-4-((R)-1-methyl-butylsulfanyl)-benzene 
• 96412-95-2 (E)-4-Methyl-1-phenyl-hept-1-en-3-one 
• 73177-67-0 2-methyl-1-phenyl-1-pentanol 

Relevant articles and documents

FUSED HETEROCYCLIC COMPOUND AND USE THEREOF

The present invention relates to a serotonin 5-HT2C receptor activator containing a compound represented by the formula wherein ring A is a 5- or 6-membered aromatic heterocycle optionally having substituent(s), and ring B is a 7- to 9-membered