57355-89-2Relevant articles and documents
Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones: Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones
Walter, Magnus W.,Adlington, Robert M.,Baldwin, Jack E.,Schofield, Christopher J.
, p. 5179 - 5192 (2007/10/03)
(Trifluoromethyl)trimethylsilane (TMS-CF3, the Ruppert Reagent) reacts with a variety of amino acid derived N-substituted oxazolidin-5-ones in excellent yields. Mild acid hydrolysis of adducts with electron-releasing substituents at C-2 affords