5737-79-1

Basic information

• Product Name: methyl 2′-amino-[1,1′-biphenyl]-4-carboxylate
• Synonyms: methyl 2′-amino-[1,1′-biphenyl]-4-carboxylate
• CAS NO: 5737-79-1
• Molecular Weight: 227.263
• Mol File: 5737-79-1.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: methyl 2′-amino-[1,1′-biphenyl]-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2′-amino-[1,1′-biphenyl]-4-carboxylate(5737-79-1)
• EPA Substance Registry System: methyl 2′-amino-[1,1′-biphenyl]-4-carboxylate(5737-79-1)

Safety Data

• Hazardous Substances Data: 5737-79-1(Hazardous Substances Data)

Upstream product

• 3215-92-7 2'-nitrobiphenyl-4-carboxylic acid 
• 98-80-6 phenylboronic acid 
• 586-76-5 4-Bromobenzoic acid 
• 92-92-2 biphenyl-4-carboxylic acid 
• 191171-55-8 2-anilineboronic acid pinacol ester 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 615-43-0 2-iodophenylamine 
• 577-19-5 2-nitrophenyl bromide 
• 615-36-1 2-bromoaniline 
• 5730-96-1 4-acetyl-2'-nitrobiphenyl 
• 86-00-0 2-nitrobiphenyl 
• 5737-78-0 methyl 2'-nitro-[1,1'-biphenyl]-4-carboxylate 

Downstream Products

• 5730-77-8 methyl 2'-amino-[1,1'-biphenyl]-4-carboxylate 
• 99585-18-9 9H-carbazole-2-carboxaldehyde 
• 873056-45-2 2-amino-4'-hydroxymethylbiphenyl 
• 2523-36-6 methyl 9H-fluorene-2-carboxylate 
• 26000-33-9 methyl 9H-carbazole-2-carboxylate 
• 857646-08-3 methyl 2'-({(2S)-5-{[(benzyloxy)carbonyl]amino}-2-[(tert-butoxycarbonyl)amino]pentanoyl}amino)-4-biphenylylcarboxylate 

Relevant articles and documents

Regioselective nitration of a biphenyl derivative to derive a fluorescent chloride sensor

Methyl 2′-aminobiphenyl-4-carboxylate, an optical chloride sensor has been synthesized via Suzuki-Miyaura cross-coupling followed by regioselective nitration. In general biphenyl systems are prone to undergo poly nitration whenever they are subjected to nitration via different nitrating agents. But in this present work, a highly selective nitration in the 2′ position of methyl biphenyl-4-carboxylate was achieved using 70% HNO3 and acetic anhydride to derive 3. Upon reduction, 3 produces 4 which shows bright blue emission in different organic solvents. In presence of chloride ion the blue emission of the sensor changes to enhanced bright green emission. The chloride sensing has also been explored using other spectroscopic techniques such as 1H NMR, UV–vis spectroscopy, and theoretical study.

Atmosphere-Controlled Palladium-Catalyzed Divergent Decarboxylative Cyclization of 2-Iodobiphenyls and α-Oxocarboxylic Acids

A novel palladium-catalyzed divergent decarboxylative cyclization of 2-iodobiphenyls and α-oxocarboxylic acids utilizing the atmosphere as a controlled switch is reported. Under the protection of a nitrogen atmosphere, tribenzotropones are synthesized by a [4 + 3] decarboxylative cyclization. Employing a palladium/O2 system enables a [4 + 2] decarboxylative cyclization to assemble triphenylenes. Notably, preliminary mechanistic studies indicate that the formation of triphenylenes involves a double decarboxylation.

Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: Synthesis of 6-alkylated phenanthridines

A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines. The use of xanthates as radical precursors allowed the synthesis of diversely 6-substituted phenanthridines. Electrophilic radicals derived from nitriles, aromatic and aliphatic ketones, malonates, and amide derivatives, as well as radicals derived from phthalimidomethyl and benzylic derivatives were successfully introduced. The reaction proceeds under mild conditions without a stoichiometric amount of oxidant. Thirty novel phenanthridine scaffolds were synthesized with yields ranging from 24 to 76%.