57397-97-4Relevant articles and documents
Highly chemo- and regioselective allylic substitution with tautomerizable heteroarenes
Kumar, Dinesh,Vemula, Sandeep R.,Cook, Gregory R.
, p. 4300 - 4306 (2015/08/11)
Tautomerizable heteroarenes, bearing multiple interconvertible nucleophilic centers exhibit high chemo- and regioselective allylation irrespective of allylating agents used under Pd-catalysis. The achieved selectivity may be attributed to the dominant lactam form of heteroarenes and Pd-catalyzed intramolecular allylic substitution. A generalized green protocol for chemo- and regioselective allylation of biologically relevant heteroarenes with allyl alcohols in dimethyl carbonate (DMC) as solvent was developed. Excellent selectivity was observed during intermolecular competition study demonstrating the differential nucleophilicity of tautomerizable heteroarenes and differential allyl palladium forming ability of a variety of allyl alcohols.
Palladium-catalyzed mono- N -allylation of unprotected anthranilic acids with allylic alcohols in aqueous media
Hikawa, Hidemasa,Yokoyama, Yuusaku
experimental part, p. 8433 - 8439 (2011/12/03)
Palladium-catalyzed N-allylation of anthranilic acids 1a-j with allyl alcohol 2a in the presence of Pd(OAc)2, sodium diphenylphosphinobenzene-3-sulfonate (TPPMS) in THF-H2O at room temperature gave only mono-N-allylated anthranilic a
Zinc Mediated Allylation of Azides: A Novel Method for the High Yield Preparation of N-Allylamines
Kumar, H. M. Samapath,Anjaneyulu, S.,Reddy, B. V. Subba,Yadav, J. S.
, p. 551 - 552 (2007/10/03)
A quick and efficient approach for mono N-allylamines has been developed by the reaction of allyl zinc reagent with alkyl and aryl azides in DMF. - Keywords: azides; zinc; DMF; allylamine
