574-13-0

Basic information

• Product Name: (E)-2-hydroxy-1,2-diphenylethan-1-one oxime
• Synonyms: Einecs 209-367-3;Ethanone, 2-hydroxy-1,2-diphenyl-, 1-oxime, (1E)-;Ethanone, 2-hydroxy-1,2-diphenyl-, oxime, (1E)-;alpha-benzoinoxime95+%;2-Hydroxy-1,2-diphenylethanone (E)-oxime;(E)-2-Hydroxy-1,2-diphenylethanone oxime
• CAS NO: 574-13-0
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.262
• EINECS: 209-367-3
• Mol File: 574-13-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-2-hydroxy-1,2-diphenylethan-1-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-hydroxy-1,2-diphenylethan-1-one oxime(574-13-0)
• EPA Substance Registry System: (E)-2-hydroxy-1,2-diphenylethan-1-one oxime(574-13-0)

Safety Data

• Hazardous Substances Data: 574-13-0(Hazardous Substances Data)

Usage

General Description

(E)-2-hydroxy-1,2-diphenylethan-1-one oxime, also known as benzophenone oxime, is a chemical compound with a molecular formula C14H13NO. It is commonly used as a photoinitiator in the production of polymers and coatings. (E)-2-hydroxy-1,2-diphenylethan-1-one oxime has been shown to have antioxidant properties and is being studied for its potential use in pharmaceutical applications. It is also used as a UV absorber in various cosmetic and personal care products. While it is considered to be relatively safe for use in these applications, further research is needed to fully understand its potential effects on human health and the environment.

InChI:InChI=1/C14H13NO2/c16-14(12-9-5-2-6-10-12)13(15-17)11-7-3-1-4-8-11/h1-10,14,16-17H/b15-13+

Upstream product

• 64-17-5 ethanol 
• 53823-87-3 (+/-)-benzoin-(O-acetyl-seqcis-oxime ) 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 7110-50-1 (+-)-benzoin-(Z)-oxime 
• 574-15-2 benzilmonoxime 
• 574-15-2 (E)-benzil monooxime 
• 555-31-7 aluminum isopropoxide 
• 5928-66-5 (R)-benzoin 
• 441-38-3 benzoin oxime 
• 5928-67-6 (S)-(+)-benzoin 
• 451-40-1 phenyl benzyl ketone 
• 118298-90-1 Trifluoro-acetic acid (S)-2-oxo-1,2-diphenyl-ethyl ester 

Downstream Products

• 4410-33-7 N-phenyl-2-hydroxy-4-phenylacetamide 
• 15582-91-9 2-phenyl-3H-indole N-oxide 
• 484-47-9 lophine 
• 13591-33-8 benzonitrolic acid 
• 642-04-6 2,3,5,6-tetraphenylpyrazine 
• 530-36-9 erythro-2-amino-1,2-diphenylethanol 
• 530-36-9 threo-1,2-diphenyl-2-aminoethan-1-ol 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 24561-41-9 (+/-)-benzoin-(O-benzoyl-seqtrans-oxime ) 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 100-52-7 benzaldehyde 
• 102-08-9 N,N-diphenylthiourea 
• 102-07-8 bis(diphenyl)urea 
• 642-36-4 4,5-diphenyl-1,3-dihydro-imidazol-2-one 

Relevant articles and documents

Readily available ruthenium complex for efficient dynamic kinetic resolution of aromatic α-hydroxy ketones

A ruthenium complex formed from commercially available [Ru(p-cymene)Cl 2]2 and 1,4-bis(diphenylphosphino)butane catalyzes the racemization of aromatic α-hydroxy ketones very efficiently at room temperature. The racemization is fully compatible with a kinetic resolution catalyzed by a lipase from Pseudomonas stutzeri. This is the first example of dynamic kinetic resolution of α-hydroxy ketones at ambient temperature in which the metal and enzyme catalysts work in concert in one pot at room temperature to give quantitative yields of esters of α-hydroxy ketones with very high enantioselectivity.

Lipase TL-mediated kinetic resolution of benzoin: Facile synthesis of (1R,2S)-erythro-2-amino-1,2-diphenylethanol

The lipase TL-mediated kinetic resolution of (±)-benzoin (1) proceeded to give the corresponding optically pure benzoin (R)-1. On the other hand, (S)-benzoin-O-acetate (5) could be hydrolyzed without epimerization to give (S)-benzoin (S)-1, under alkaline conditions. Further, (R)-1 was converted to (1R,2S)-2-amino-1,2-diphenylethanol (99:1 er) according to the procedure reported previously. (C) 2000 Elsevier Science Ltd.

Asymmetric Synthesis of the Methyl and Benzyl Ethers of erythro-α,β-Diphenyl-β-hydroxyethanol and erythro-α,β-Diphenyl-β-hydroxyethylamine from (+)-(S)-Benzoin

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